SKU: 21403797289

mNSET™ (Non-Surgical Embryo Transfer) Device for Mice 60010 (10 Devices per box)

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Ships within 48 hours · Estimated delivery Aug 18 - Aug 23

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Description

mNSET™ (Non-Surgical Embryo Transfer) Device for Mice 60010 (10 Devices per box)mNSET ordered after June 24, 2026 will ship on July 7, 2026 For AI and pathogen transfer, see product 60020. 10 Devices Box ParaTechs mNSET (Non Surgical Embryo Transfer) Device for Mice 60010 revolutionizes mouse uterine embryo transfer by reducing cost and eliminates the need for animal anesthesia and recovery normally required for conventional surgical procedures. Compare this methodology with the time, expense, and training required to accomplish

mNSET ordered after June 24, 2026 will ship on July 7, 2026

For AI and pathogen transfer, see product 60020.

10 Devices/Box

ParaTechs’ mNSET™ (Non-Surgical Embryo Transfer) Device for Mice 60010 revolutionizes mouse uterine embryo transfer by reducing cost and eliminates the need for animal anesthesia and recovery normally required for conventional surgical procedures. Compare this methodology with the time, expense, and training required to accomplish the same task with other methods and you will discover that the NSET procedure is humane, quick, and cost effective.

The mNSET Device for Mice 60010 is manufactured in the USA, solely for ParaTechs Corporation, and is EtO (Ethylene Oxide) sterilization processed. Patent Information: Non-Surgical Embryo Transfer Method and Apparatus, United States Patent 9,615,903. [PDF]

 Harmonized Tariff: 3926.90.9910

Based on user feedback, we would like to emphasize the following observation: 

The mNSET hub must be firmly seated on the P2 pipette to effectively uptake and dispense liquid.  Please be sure to firmly attach the device using pressure and a slight twisting motion.  This will ensure proper placement.

10% Discount on orders of 10 or more boxes. Discount applies automatically at checkout. 


mNSET 60010 Videos

Watch the mouse NSET demonstration videos:

  1. mNSET 60010 Full Procedure Demonstration Video
  2. mNSET 60010 Quick Procedure Only Video

Watch ParaTechs' JoVE article "Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination"  

  1. Author Spotlight
  2. Cervical Manipulation Procedure for Use with Artificial Insemination in CD1 Mice (CM Rod 90050) (mC&I Device 60020)
  3. Non-Surgical Embryo Transfer Procedure for Use with Cervical Manipulation in CD1 Mice (CM Rod 90050) (mNSET Device 60010)

Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination JoVE Published: July 7, 2023

mNSET 60010 Webinars

Watch both webinars presented by Dr. Barbara Stone, Director of Rodent Assisted Reproductive Technologies, ParaTechs Corporation

  1. Rodent Embryo Transfer and the 3Rs
  2. The Future of Mouse Embryo Transfer: Achieving the 3Rs with the NSET Device

Labroots Webinar ABSTRACT: Non-surgical transfer techniques for mouse embryos and sperm provide animal welfare benefits for assisted reproduction of mice. While surgical embryo transfer (ET) is an effective method for transfer of embryos into the uterine horn of mice, surgery is expensive, time consuming, and requires technical expertise. Surgery is also a stressful procedure for the mouse, which has to be anesthetized and treated with an analgesic. We have developed a simple, brief procedure for ET using a non-surgical embryo transfer (NSET) device. Once embryos are loaded into the NSET device, the NSET catheter passes through the vagina and traverses the cervix to deposit the embryos into the uterine horn of a recipient mouse. Since the NSET procedure does not require sedation, opening of the inner body cavity, or use of an analgesic, this procedure is less stressful for the mouse than surgery. In proof, our results show that when pseudopregnant mice are monitored by electrocardiography, the non-surgical procedure does not affect heart rate. The NSET procedure also has no effect on the level of the stress biomarker fecal corticosterone measured by ELISA analysis. However, surgery or anesthesia does lower heart rate and increases levels of fecal corticosterone. Additional studies show that the NSET procedure is effective for transfer of mouse embryos for the purposes of rederivation, cryorecovery, and transgenic research. Embryos can be successfully transferred with the NSET technique after cryopreservation, in vitro fertilization (IVF), or embryonic stem (ES) cell injection as an alternative to traditional surgical embryo transfer. The NSET device has also successfully transferred mouse sperm for artificial insemination. Therefore, the NSET technique is an example of a 3Rs refinement, an alternative to a surgical procedure, which will lead the way for improved assisted reproductive techniques in mice. 


Uses

Mouse Embryo Transfer:

  • Embryo transfer after DNA microinjection
  • ES cell chimeric blastocyst transfer
  • Cryopreserved embryo transfer
  • Embryo transfer after in vitro fertilization
  • Embryo transfer for rederivation

Other:

  • Small volume material transfer to the uterine horn.  For larger volume transfer, please consider the mC&I device which has a 40µl capacity. 
  • Mouse Sperm Transfer for Artificial Insemination (AI): Fresh sperm
  • Pathogen Transfer: Chlamydia trachomatis
  • Material Transfer:
    • Decidualization procedures
    • Pharmaceuticals

Advantages

  • Eliminates the pain and distress of surgery
  • No anesthesia required
  • Eliminates need for post-surgical monitoring of animals
  • Reduces regulatory burden by eliminating need to justify survival surgery
  • Eliminates surgical instruments and time-consuming pre- and post-surgical processes
  • Greatly reduces time required to become proficient in embryo transfer or artificial insemination (AI)
  • Reduces costs of embryo transfer
  • Reduces costs of AI
  • Easy procedure
  • Convenient
  • Sterile and ready to use
  • 3Rs implementation (Reduce & Refine)

Documents

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 21403797289

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Nana
Grantham, US
★★★★★ 4
Chuckit medium rebound balls
Size: Medium
My 8 month old German shepherd dog loves these balls. They are easy to throw, they bounce great, they are very chewable! She keeps one in her mouth most of the time. It satisfies her need to chew and she does not chew other things. She drops it in the water and lets the hole fill up and drinks that way. The only problem that has caused is suction in her mouth and difficulty in dislodging it for her. However, she would be lost without it!
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Reviewed in the United States on April 19, 2023
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Helena
Phoenix, US
★★★★★ 5
These are definitely indestructible
Size: Medium
Both of my dogs can destroy a ball in a matter of minutes if I let them play with them (supervised) as is. Well not with these balls. They are the ONLY ones I have found that are 100% indestructible. Please only let your dogs play with these as a toy when supervised though. They go really far when throwing them, so both dogs get a good amount of running and exercise with these. I also bought these because they have the hole in the middle of the ball which is very important in the event that a dog gets one stuck at the back of their throat. This allows them to breath unlike those without this hold. It's an unlikely event, but as dog owners, we all need to be aware of this and educate ourselves on what to do if this SHOULD happen. This isn't a scare tactic, nor a reflection of this particular brand, it can happen with any type of ball. My two dogs are about 45ish lbs and the size is perfect for them, I don't want anything smaller than this. They love them. There is no annoying squeak. Really easy to wash after use. Some balls take forever to get the slimy saliva off, but these don't.
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Reviewed in the United States on September 25, 2025
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Ale quintero
San Leandro, US
★★★★★ 5
He loves this ball
Size: Medium, Size: Medium
My dog loves this ball. It’s the perfect size, he enjoys playing fetch and this ball has been his fav one. Thank you guys for making my lil one happy
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Reviewed in the United States on May 2, 2026
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Secret Angel
Pawtucket, US
★★★★★ 5
Transformative for Dry, Cracked Heels!
Color: Original Grey
I recently purchased Dr. Frederick's Original Moisturizing Heel Socks, and they have truly transformed the condition of my feet! I can’t recommend them highly enough. Effective Moisturization: These socks are infused with moisturizing agents that work wonders. After just a few uses, I noticed a significant reduction in dryness and cracking on my heels. My feet feel softer and smoother, and I love that I can wake up to beautifully moisturized skin. Comfortable Fit: The socks are incredibly comfortable to wear, with a snug yet gentle fit. I appreciate that they don’t feel restrictive, allowing me to walk around my home while wearing them without any discomfort. They are also lightweight, making them easy to slip on before bed. User-Friendly: They are super easy to use—just wear them overnight, and let the socks do their magic. I love the simplicity of incorporating them into my nighttime routine. Durable Quality: The quality of the socks is impressive. They wash well and have maintained their shape and effectiveness after multiple uses. I feel confident that they will last a long time. Final Thoughts: If you're struggling with dry, cracked heels, I highly recommend Dr. Frederick's Original Moisturizing Heel Socks. They are a fantastic investment in foot care and have made a noticeable difference in the health of my skin. These socks have become a must-have in my self-care routine!
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Reviewed in the United States on October 4, 2024
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Donna
Grantham, US
★★★★★ 5
These worked for me!
Color: Original Grey
They worked great. I bought these for cracked sore heels. It took 2-3 weeks but my heels no longer hurt and the cracks have closed and look more like an indention than a crack now. They feel so much better, but I'll probably wear them another week just to be sure they stay healed. They look and feel like regular socks from the outside but only cover the heel with the toe open. Not think but not thick, again like regular socks. They would probably be slippery on a smooth surface the same as socks. The inside feels like rubber or something smooth at the heel. I have washed them once each pair and accidentally dried one pair in the dryer. They still seem to feel the same so I think they're fine. They're pretty inexpensive and had different colors and sizes.
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Reviewed in the United States on February 10, 2026

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