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Description
Natural Factors DGL 400mg - 90 Chewable TabletsDGL stimulates and or accelerates the factors that protect against ulcer including increasing the production of mucin the protective coating in the stomach and intestines. Numerous studies over the years have found DGL to be an effective anti ulcer compound. In several head to head comparison studies, DGL has been shown to be more effective than either Tagamet, Zantac or antacids in both short term treatment and maintenance therapy of gastric and
DGL stimulates and/or accelerates the factors that protect against ulcer including increasing the production of mucin – the protective coating in the stomach and intestines.
Numerous studies over the years have found DGL to be an effective anti-ulcer compound. In several head to head comparison studies, DGL has been shown to be more effective than either Tagamet, Zantac or antacids in both short-term treatment and maintenance therapy of gastric and duodenal ulcers.
Numerous studies over the years have found DGL to be an effective anti-ulcer compound. In several head to head comparison studies, DGL has been shown to be more effective than either Tagamet, Zantac or antacids in both short-term treatment and maintenance therapy of gastric and duodenal ulcers.
DGL is composed of several flavonoids that have been shown to inhibit H. pylori.
Main selling features
- As effective as antacid drugs for healing gastric ulcers and preventing their recurrence
- Helps prevent the occurrence of ulcers
- Inhibits the growth of H. pylori bacteria
- Soothes inflamed and damaged mucous lining, and promotes healing
- Doesn’t inhibit the production of stomach acids
- Deglycyrrhizinated licorice is free from the potentially serious side effects of whole licorice root
- Chewable tablets ensure the DGL is activated by the saliva
How it works
When you are experiencing the discomfort of ulcers or stomach upset, antacids can temporarily inhibit the production of stomach acid, which can ease the burning of sensitive mucous membranes. But this only addresses the symptoms.
Deglycyrrhizinated licorice root extract (DGL) offers a more rational approach by actually promoting healing. Licorice contains antioxidant flavonoids that help heal digestive tract cells. It supports stomach cells that produce mucin to protect the lining of the stomach. It also stimulates the growth of new mucosal cells. The flavonoids in DGL also inhibit a bacterium, Helicobacter pylori, that grows in the stomach and is believed to play a role in causing some stomach ulcers and chronic gastritis (inflammation of the stomach lining).
As mentioned above, DGL is a preparation of licorice from which the compound glycyrrhizin has been removed. In large doses, glycyrrhizin can cause hypokalemia, a drop in the level of potassium in the blood stream. This can lead to hypertension (high blood pressure). These side effects are triggered because glycyrrhizin acts like the adrenal hormone aldosterone, causing sodium retention which results in an expansion of the body’s fluid volume and an increase in blood pressure.
Deglycyrrhizinated licorice root extract (DGL) offers a more rational approach by actually promoting healing. Licorice contains antioxidant flavonoids that help heal digestive tract cells. It supports stomach cells that produce mucin to protect the lining of the stomach. It also stimulates the growth of new mucosal cells. The flavonoids in DGL also inhibit a bacterium, Helicobacter pylori, that grows in the stomach and is believed to play a role in causing some stomach ulcers and chronic gastritis (inflammation of the stomach lining).
As mentioned above, DGL is a preparation of licorice from which the compound glycyrrhizin has been removed. In large doses, glycyrrhizin can cause hypokalemia, a drop in the level of potassium in the blood stream. This can lead to hypertension (high blood pressure). These side effects are triggered because glycyrrhizin acts like the adrenal hormone aldosterone, causing sodium retention which results in an expansion of the body’s fluid volume and an increase in blood pressure.
Ingredients
| Each Tablet Contains: | |
| Deglycyrrhizinated Licorice 10:1 Extract | |
| (Glycyrrhiza glabra) (root) | 400 mg |
| Providing 4000 mg crude herb licorice |
Non-medicinal ingredients
Dextrose, microcrystalline cellulose, guar gum, purified water, stearic acid, vegetable grade magnesium stearate (lubricant).
Suggested Usage
Chew 1 tablet up to 3 times per day 20 minutes before each meal or as directed by a health professional.
Additional Information
DGL Research Information (pdf)
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4.4 ★★★★★
Based on 12 reviews
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Product Reviews
★★★★★ 4
My kitten loves this ball
I originally got this for my 14-year-old dog because he has always loved balls, and I thought it might be a fun way to provide a little extra stimulation and entertainment.
Unfortunately, he didn’t show much interest in it. However, I honestly think that may have had more to do with his age than the toy itself.
The surprise was my kitten. She absolutely loved it and spent quite a bit of time chasing, batting, and interacting with it. Once she figured out that touching it would make it move, it really seemed to hold her attention.
I mainly used the passive mode, where the toy only moves after being touched. I liked this setting because it felt less overwhelming and encouraged interaction without constantly running around on its own.
Based on my experience, I think this toy is best suited for younger, curious pets that enjoy investigating moving objects. While it wasn’t a hit with my senior dog, it was definitely a success with my kitten.
Overall, it seems well made, easy to use, and a fun option for playful pets.
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Reviewed in the United States on June 8, 2026
★★★★★ 5
My Puppy Loves this Indestructible Dragon
Size: Large, Color: Pink, Size: Large, Color: Pink
My puppy (8 month old black lab mix) loves, loves, loves her dragon. She has had it for 2 months now. It is one of her favorites and gets daily rough play time. It's her go-to toy for fetch and tug games, as well as just general mouthy play. The squeaker gave out after about 4 weeks, but she would binge squeak for prolonged periods (kind of like chomping on gum) so it was almost a blessing when it went silent. She still chomps on it, but at least now I don't have to hear it. Other than the fact that it's a little grungy and bedraggled from so much loving, it is still in amazing shape. The seams and fur are all still intact. There are no visible holes, rips, or weak spots. I love Chew Guard Technology.
This dragon replaced her goDog Iguana (from PetSmart) that developed a tear in the fur after about 4 months of heavy use. (It was superficial, just the outer fur layer and not the innards, but we disposed of it before she could eat more fur.) She can be pretty rough on her toys and I can never predict if any given toy will last minutes or months. The goDog stuffies definitely fall into the "months" category, even with rough daily use.
Edit: The dragon lasted about 6 months of intensive, hard play before it developed a small tear in the fur. I patched it a couple times, but once my pup discovers a weak spot, it's the kiss of death for any stuffed item. We had to dispose of the dragon (so sad) to keep her from eating any more of the fur. We replaced the dragon with the goDog Chameleon, which is still going strong. I think we will go back to the dragon for our next toy because it's just so darned cute. We gave the dragon to my niece for her golden retriever puppy who is very chew-happy. That dragon is also doing well. You've just gotta love that chew-guard technology. This is one tough toy.
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Reviewed in the United States on September 26, 2015
★★★★★ 5
Precious toy for big dogs too
Size: Large, Color: Skinny Green
Not only is this toy cute and fun, but material is thick and durable even for my crazy GSP who is a destruction artist. This is, the favorite toy his go to in the toy box.
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Reviewed in the United States on May 15, 2026
★★★★★ 5
Indestructible Toys My Dobermans ❤️
Size: Large, Color: Mesh Green
Actually Respect! goDog Is a Lifesaver
The variety of size and colors are phenomenal 😇
I have two Dobermans — serious, determined power chewers — and I’ve spent years trying to find toys that survive even a few days.
I’ve tried the big brands (Kong, Goughnuts, Jolly Ball, you name it) — and while some toys last a little while, almost everything eventually ends up shredded, de-squeaked, or in pieces.
goDog toys are the ONLY plush toys my Dobermans won’t destroy.
We own multiple goDog toys now — dragons, dinosaurs, lizards — mostly in the large size (perfect for Dobermans), but even a few medium-sized ones hold up surprisingly well.
Here’s what’s amazing:
• They love them — actually carry them around, toss them, chew them gently, and squeak them happily.
• They do not rip them apart — no matter how much tugging, chewing, or wrestling happens.
• Large sizes are best for Dobermans (and other big breeds) — but even mediums survive for calmer play sessions.
• No ripped seams, no stuffing everywhere, and no destroyed squeakers after months of use.
What makes goDog toys different?
The secret is their Chew Guard Technology —
• A reinforced, high-strength inner mesh layer under the soft plush
• Double-stitched seams
• Durable yet flexible material that somehow resists punctures, tears, and brutal shaking
The outside stays soft and fun, but the inside is built like armor.
It’s NOT a super hard rubber or rough canvas — it still feels like a cuddle toy, but it’s engineered to survive serious chewing.
Materials include:
• Durable polyester plush
• Chew Guard inner lining (high-tensile mesh fabric)
• Reinforced stitching
• Non-toxic squeakers
• Safe for dogs to play with long-term
Real Owner Advice:
• Always size up if you have a heavy chewer — large sizes are a must for Dobermans or similarly strong breeds.
• Medium sizes are fine if you supervise or your dog is more moderate with toys, but the large toys are built tougher overall.
Final Thoughts:
If you have big dogs, strong jaws, or just tired of wasting money on destroyed toys — goDog toys are a must.
No other plush-style toy even comes close.
My Dobermans will destroy almost anything… but they treat their goDog toys like treasured companions. No holes, no rips, just happy dogs.
Follow me here on Amazon for more honest, dog-tested reviews! Like this review if it helped — I’ll be uploading even more proven tough toys and pet essentials soon!
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Reviewed in the United States on April 29, 2025
★★★★★ 4
Surface Fabric is very durable
Size: Small, Color: Hot Pink
Surface Fabric is very durable, but the squeaker didn't last two months. I have urged the manufacturer to find a strong more durable squeaker for their product. My dogs really enoys it when the speaker works. One of his 3 work. I have just bought two more he likes them so much. He takes it to bed every night to catch it once or twice before sleeping. Also loves to catch it a few times during the day.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026
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