SKU: 19773956515

Core Nutritionals 5-AT

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Description

Core Nutritionals 5-AT5 Etioallocholen 3b,7b,17b triol: More commonly known as androstenetriol, 5 etioallocholen 3 beta 7 beta 17beta triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex

5-Etioallocholen-3b,7b,17b-triol: More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

1. Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
2. Preventing muscle protein synthesis.
3. The breakdown of glycogen (the compound responsible for that “full look”).
4. Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol: In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

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SKU: 19773956515

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4.8 ★★★★★
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P Scott
Omaha, US
★★★★★ 5
Cooling and comfortable pillow cover
Color: White, Size: Queen
This is a very nice pillow cover. It’s very well made, has a zipper and the fabric is what I consider as plush. It’s very pretty but I use it under the pillow case. The best feature to me is that it keeps my head cool. I sleep on a latex pillow and they are usually too warm for me.
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Reviewed in the United States on May 16, 2026
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Verified Purchase
Egle Patamsyte
Los Angeles, US
★★★★★ 5
Pillow case
Color: White, Size: Body
Here is another example of a review about a pillow case that matches your description: I ordered this pillowcase because I needed a pillow case on my special body pillow-that was long, cozy, and soft. I was not disappointed. These pillow case are made from 100% organic bamboo viscose, which is hypoallergenic, breathable, and silky smooth. They have a special shape that fits my extra-long pillow perfectly, and it doesn’t slip off or bunch up. This is also very easy to care for, as it is machine washable and wrinkle resistant. I like chose the white one because it looks elegant and fresh. This pillowcase definitely worth the price, and I would recommend it to anyone who wants a high-quality pillow case that is long, cozy, and soft.
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Reviewed in the United States on December 29, 2023
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Verified Purchase
Neal
Dallas, US
★★★★★ 5
Wonderful pillow and products!
Color: White, Size: Body
I've been using the Snuggle-Pedic pillow for a couple of weeks now, and it is fantastic. It's soft, but the foam is firm and full. It is clearly extremely well made. Everything from Snuggle-Pedic appears to be top quality, right down to the extra little instructional inserts they include with their products. I also purchased the Zipper Removable Cover to make laundering easier. It's just as well made as the pillow. In fact, it's exactly the same as the cover on the pillow except removable due to the zipper. I'm also using the Snuggle-Pedic Organic Cotton Pillow Case, and it too is extremely well made, soft and comfortable. I was a little hesitant about the pillow case when I saw the picture because it almost looked ... too soft for me, sort of like a fleece blanket. Maybe that was just the way I saw the picture, but it's not actually like fleece. It's very soft and comfortable and does stretch a little as opposed to a regular pillow case, as they say in the description, but in a good way and appears very durable. I was concerned that it would stretch out and twist around the pillow, but it doesn't do that at all. It has stayed perfectly fitted to the pillow. From what I've experienced, everything in the descriptions of the Snuggle-Pedic products is true, and all three pieces work perfectly for me. This is the most I've spent on an individual pillow, but I couldn't be more pleased, and I'm planning to replace all my pillows.
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Reviewed in the United States on August 16, 2016
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Verified Purchase
Derek
Grantham, US
★★★★★ 4
Cool Slumberings
Color: White, Size: Queen
For transparency, I was given this pillowcase to review by Relief Mart. However all views are my own and not biased because of it. I had recently purchased the matching pillow (see my other review) and had the opportunity to try this out. In terms of specs, it's basically made out of the same material as the Snuggle-Pedic Bamboo Shredded Memory Foam Pillow - it even has the same woven design. According to manufacturer claims: 'Soft and Luxurious Kool-Flow® Micro-Vented Bamboo Cover' - The pillowcase material is very soft to the touch, and does have a premium feel to it. It did have a slight 'smell' when it first arrived, however once washed (and air dried) it's not there anymore. 'Unprecedented breathability that allows air to circulate through the pillow' - It definitely keeps a certain 'coolness' and doesn't heat up if you stay in one spot. It makes staying still bearable, as I'm a sleeper always looking for the cooler side of the pillow during the night. As described, it's zippable so you can separately wash it from the pillow, and I can attest that it does keep it's softness and fluffliness after 3 weeks of use. Though I'm very happy with it, there's a couple things to build on in my opinion: - color and texture of fabric. By itself, the look of the pillow makes it seem that there's no pillowcase. So if you're picky about your bedsheets when you make your bed, this pillowcase will probably stick out like a sore thumb. The unsubtle branding and slight off white coloring doesn't help as well. - there's a tag outside the pillowcase near the zipper, and though it doesn't affect it in any way, it can be slightly annoying and aesthetically displeasing as it sticks out a bit. Would suggest placing it on the inside. I would definitely recommend this product, irrespective of the (minor) points above, as this has made my slumbering experience a whole lot better.
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Reviewed in the United States on June 16, 2016
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Verified Purchase
M.H.
Fort Morgan, US
★★★★★ 5
Great pillow case from a company that cares!
Color: White, Size: Body
The Snuggle-Pedic Body Pillow Case is GREAT and is the perfect pillow case for their body pillow! Feels exactly like the great material that's on the body pillow (soft and breathable) -- and it fits the pillow perfectly! I love that there's a zipper on it as I don't have to deal with the pillow slipping out of the case at all. The case fits perfectly and is the perfect case for the pillow! I read some other reviews where people said they didn't love that the tag/label was on the opposite side of the zipper on the case. But for me this was a non-issue. I cut the tag off and now there's no issue at all. :) Oh, and I have to give a shout out to Snuggle-Pedic and their company....they are awesome! They did offer me a free case in exchange for an honest review. But this isn't what I think they are awesome for. I find them to be a stand up company that is truly there to support their customers! They include a little note when you get the pillow and pillow case giving you their phone number and letting them know they are here to help if we have any questions. And they send an email as well saying they are available if we have any questions and they gave suggestions on how to care for their products. They are quick to respond and truly lovely people. I'm a sucker for supporting good companies....companies that actually truly care about their customers...and this company is that! I highly recommend this product :)
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Reviewed in the United States on June 2, 2016

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