SKU: 32113580338

SkinMedica HA5® HYDRA COLLAGEN Replenish + Restore Hydrator

Sale price$172.80 Regular price$192.00
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Description

SkinMedica HA5® HYDRA COLLAGEN Replenish + Restore HydratorAn Evolution in Hydration Introducing the next gen HA, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE Technology to replenish natural humectants, including HA and help restore skin's hydration reservoir. Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier looking skin with fewer lines. Silicone free Non comedogenic Sulfate free

 

An Evolution in Hydration – Introducing the next-gen HA⁵®, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE® Technology to replenish natural humectants, including HA and help restore skin's hydration reservoir.

Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier-looking skin with fewer lines.

Silicone-free • Non-comedogenic • Sulfate-free • Lightweight • Fragrance-free • Paraben-free • Pilling-free

Store at room temperature 15°C - 30°C (59°F - 86°F).

Key Benefits

  • HA⁵® Hydra Collagen Replenish + Restore Hydrator attracts and retains water for instant hydration and visibly plump, smooth skin
  • In a clinical study, patients reported they looked ~ 3 years younger by week 121
  • Clinically proven to improve hydration and support skin health by addressing the skin barrier and water-holding capacity

1. Data on file at SkinMedica®

Key Ingredients

Advanced VITISENSCE® Technology

Features a blend of nutrients found in nature, targeting existing collagens within the skin to boost hydration naturally.

  • Avocado Oil Esters - Supports skin's natural hydration and skin's water-holding abilities
  • Vitamin F - Supports skin barrier and prevents water loss
  • Passion Fruit Seed Oil - Enhances skin health and supports skin's water and nutrition flow
  • Vitis Flower Stem Extract and Lotus Sprout Extract - Protect against oxidative stress

Proprietary HA⁵® Hydra Collagen Complex

Hydration Collagen - vegan collagen that attracts and retains water for instant hydration and smoothness

 

5 Forms of HA:

  • Vectorized Time Release HA - A SkinMedica® proprietary ingredient for sustained release of HA
  • Cross-linked HA - Provides long-lasting hydration
  • Encapsulated HA - For immediate hydration
  • Noncross-linked HA - For smoothness and hydration 
  • Nano-hyaluronic acid - Soothes skin

 

How to use

  • When to Apply

    Apply twice daily— morning and at night—after cleansing and treating your skin. Use before you moisturize and apply SPF.

  • Where to Apply

    Apply to face, neck and chest, or any area needing hydration.

  • How to Apply

    Dispense 1 to 2 pumps in your palm and smooth onto the skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.

Behind the Formula:
Why it Works

HA⁵® Hydra Collagen Replenish + Restore Hydrator is our next level hydrator solution clinically proven to visibly improve hydration and support skin health, by improving the skin's barrier and water-holding capacity.

It has 2X more HA than the previous formulation to provide optimal, immediate hydration. It's our first and only hydrator to use our proprietary HA⁵® Hydra Collagen technology and Advanced VITISENSCE® Technology, targeting existing collagens deeper within the skin to boost hydration naturally. Provides long-term results that reduce the appearance of lines and redness.

 

Additional Information

  • What differentiates HA® Hydra Collagen Replenish + Restore Hydrator from the legacy HA® Rejuvenating Hydrator product?

    Modernizing our legacy HA⁵® formulation takes HA⁵® Hydra Collagen Replenish + Restore Hydrator to the next level of hydrator innovation. NEW Hydra Collagen is a vegan collagen that attracts and retains water for instant hydration and smoothness. ADVANCED VITISENSCE® TECHNOLOGY replenishes the natural HA, biohumectants, and hydration-boosting collagens within the skin to support the skin's hydration reservoir. Now, hydration lasts twice as long (48 hours vs 24 hours) compared to the original formulation.

  • What’s the difference between a moisturizer and a hydrator?

    A moisturizer is a cosmetic cream or lotion made with humectants or occlusive or a combination of that prevents skin dryness. A hydrator is a cosmetic treatment product that promotes epidermal health by supporting the skin’s natural biomolecules, including HA, other humectants and hydration-boosting collagens.

  • What’s the difference between dehydrated and dry skin?

    Dry skin is a skin type, while dehydration is a skin condition. In both, the skin undergoes transepidermal water loss, or evaporation of water from inside the body. With this water loss, the enzymes that normally help the skin shed cells cannot function properly, resulting in a buildup of cells that makes the skin look rough and dry, contributing to the appearance of fine lines and wrinkles. Dry skin can be genetic or a symptom of systemic disease. It is caused either by the inadequate production of oil, called sebum, or by an imbalance of fatty acids, ceramide, and cholesterol in the stratum corneum, the barrier layer of the skin. Age is also a factor since we experience a decline in a main hormone that triggers sebum production. Dehydrated skin still produces sebum, but is temporarily dry because of various factors, including environmental effects such as a dry climate, harsh detergents, or skin products. It is also caused by a temporary imbalance of fatty acids and ceramides in the skin’s barrier layer, resulting in a temporary spike in transepidermal water loss.

  • How should HA⁵®  Hydra Collagen Replenish & Restore Hydrator be used within a regimen?

    HA⁵®  Hydra Collagen Replenish & Restore Hydrator can be used with any SkinMedica® product or regimen to support hydration. It should be applied immediately before moisturizer in a normal regimen.

In Clinical Studies

  • 93% of patients reported this product made their skin look dewy and healthy at 2 weeks (n=30)

  • 93% reported skin looked visibly plumper at week 12 

  • 97% of patients agreed this product improved their skin quality at week 12 

  • 100% of patients agreed this product made them feel confident about their skin at week 12 

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 32113580338

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4.6 ★★★★★
Based on 26 reviews
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Verified Purchase
D. Rodriguez
Whiting, US
★★★★★ 5
Finally, a ball that made it!
Color: Blue, Color: Blue
I don’t know what is it with this ball, but it’s special. My dogs can absolutely tear up anything and this one seems like it can be chewed up but my dog loves it too much. He carries it all day, nibbles it and loves the squeaky sound of course. Finally found a winner!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2026
R
Verified Purchase
Renae
Fort Morgan, US
★★★★★ 5
Good size ball for my big boy
Color: Purple
My big boy loves this ball. He chews and chews and chews on it and it ain't made a dent in it. It's made a good quality rubber. It's got a squeaker in it. He hasn't managed to get it out which is not normal because normally he can get a squeaky out within 10 minutes. He goes through toys like I don't know what so it's being being a good. Really good ball. We've had it for about 2-3 months now and he hasn't been able to break into it and get squeaky out or even make a dent into it. That would tear up the the rubber
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 1, 2026
C
Verified Purchase
coach316dc
Carnegie, US
★★★★★ 5
Sturdy ball, holding up well.
Color: Purple
I have a ball obsessed Shih Tzu. This has become his security blanket. He literally takes it everywhere and even sleeps with it next to him. Dexter loves any ball. All shapes and sizes. He will play fetch all day long if you let him. He doesn't know when to quit. It can be 100 degrees out with 80% humidity and he'll fetch all day long. This is a larger ball, I think just over 3 inches. It is entirely too big for a Shih Tzu, but it is perfect for Dexter. He came to us with a ball similar to this that he has since lost. He carries it in his mouth by placing his incisors in the indentations and lets it hang out the side of his mouth. Quite comical actually, but it works for him. We have bought him balls more for his size, but they're too small and he gets them lost under cabinets, furniture or any nook and cranny the ball will fit. And being obsessive, he will bark and carry on because he can't get to the ball until you come and rescue it. Difficult on our old knees. So he ends up getting the smaller balls taken away from him. The other night he was laying and chewing on this ball. It sounded like he was shredding this ball to pieces. I was afraid he would choke or swallow the rubber pieces, so I took it away from him. There wasn't anything wrong with the ball. It looked brand new. No chew or bite marks that I could see. I was impressed. It does have a squeaker, but I can barely get it to squeak and I have strong hands. A larger dog with a stronger bite force could probably easily make it squeak. It claims to have a beef scent to the toy, and maybe that is why he likes the ball so much. But I sniffed it and couldn't smell anything, which is fine by me, it won't have an obnoxious smell to where I don't want it around me.
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Reviewed in the United States on December 7, 2025
T
Verified Purchase
T W
Phoenix, US
★★★★★ 5
Dogs love balls
Color: Orange
Most dogs love to play with balls. This is a ball. It squeaks and can handle a lot of strong chewing. Quite durable and a good size for medium and up sized dogs. (Honestly even smaller dogs would have fun with this).
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Reviewed in the United States on April 23, 2026
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Verified Purchase
shaylynn filiault
Birmingham, US
★★★★★ 5
Good quality
Color: Green and Purple
Good quality and last long. Is loud wheen squeeks
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 16, 2026

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