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Description
Claudin 18.2 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (S-102-24)Product Specification Host Rabbit Antigen Claudin 18. 2 Synonyms CLDN18. 2 Immunogen Synthetic Peptide Location Cytoplasm, Cell membrane Accession P56856 2 Clone Number S 102 24 Antibody Type Recombinant mAb Isotype IgG Application IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 01% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Antigen | Claudin 18.2 |
| Synonyms | CLDN18.2 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cell membrane |
| Accession | P56856-2 |
| Clone Number | S-102-24 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| IF | 1:200 | null |
Background
Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. Claudin 18.2 is involved in tumor development and progression and located in the outer cell membrane. It has exposed extracellular loops and is available for monoclonal antibody binding.
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