SKU: 1203048027

PerCP-Cy5.5 Rat Anti-Mouse F4/80 Antibody (S-R537)

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Description

PerCP-Cy5.5 Rat Anti-Mouse F4/80 Antibody (S-R537)Product Specification Host Rat Antigen F4 80 Synonyms Adhesion G protein coupled receptor E1; Cell surface glycoprotein F4 80; EGF like module receptor 1; EGF like module containing mucin like hormone receptor like 1; EMR1 hormone receptor; Emr1; Gpf480; Adgre1 Location Cell membrane Accession Q61549 Clone Number S R537 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample Mouse peritoneal exudates cells Purification

Product Specification


Host Rat
Antigen F4/80
Synonyms Adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; Emr1; Gpf480; Adgre1
Location Cell membrane
Accession Q61549
Clone Number S-R537
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample Mouse peritoneal exudates cells
Purification Protein G
Concentration 0.2 mg/ml
Conjugation PerCP-Cy5.5
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

F4/80, also known as ADGRE1 or EMR1, is a cell surface glycoprotein and a member of the EGF-TM7 protein family. It is widely used as a marker for mature mouse macrophages and is highly expressed in various macrophage populations, such as Kupffer cells in the liver, Langerhans cells in the skin, and microglial cells in the brain. However, its expression in human cells is different, being mainly found in eosinophils and some macrophages. F4/80 is an orphan receptor involved in cell adhesion and immune cell interactions, and it may also play a role in the development of regulatory T cells. The protein has a large extracellular domain containing multiple EGF-like calcium-binding domains, linked to a seven-transmembrane domain characteristic of G protein-coupled receptors.

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SKU: 1203048027

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4.4 ★★★★★
Based on 21 reviews
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Product Reviews
R
Verified Purchase
R. Church
Charlottesville, US
★★★★★ 1
My dog's favorite toy, but
Size: 15 Inch
My dog loves his "lizzie" but the quality has gone down. The leather is thinner and easily torn, exposing the squeaker which becomes a swallowing hazard. Of course, no squeaker and half the fun is gone. For $10, I won't be buying any more of these. Sorry about that my furry friend.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 20, 2026
H
Verified Purchase
Heidi G
Pawtucket, US
★★★★★ 5
Almost as good a chewing on my belt.
Size: 25 Inch
My corgi has always loved chasing her leash or a belt so I thought the snake would be a good fit for her. It quickly became her favorite. The squeakers lasted for maybe a month? Once there was a hole then we took them all out so she wouldn't choke. The snake without the squeakers is still a favorite. She's been chewing the tail end consistently and likes to lick it for some reason. I recommend this as a good tug toy. I like that it was made of leather.
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Reviewed in the United States on April 6, 2026
N
Verified Purchase
ncgirl
Alexandria, US
★★★★★ 3
DISAPPOINTED
Size: 25 Inch, Size: 25 Inch
I've bought this 9 times since it's my Maltipoos' favorite toy! Unfortunately the one that just came in is not up to par as those previously bought. The leather was cut sloppily & the sewing sometimes ran off the leather completely or so close to edges could easily be chewed open. I can't send back because bought as a treat before leaving for trip & the fact he's already seen it ! I used sewing machine to sew areas that were close to edges - had to take out stitches to remove top squeaker to be able to sew around that area on both sides. Don't know how long this one will last even though I used quilting thread which is a bit stronger than regular thread. Hope this was just a bad one & if so, wish company's quality control would have caught this & rejected it.
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Reviewed in the United States on March 21, 2026
K
Verified Purchase
KJ
Louisville, US
★★★★★ 4
Not for aggressive chewers
Size: 36 Inch
My GSD ate half of it within 20min before I caught her. I don’t think it was meant for aggressive chewers so I can’t fault the product for that. My dogs did have a few hours of fun with it playing tug and it held up well.
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Reviewed in the United States on October 9, 2025
E
Verified Purchase
EWE
Dallas, US
★★★★★ 5
Doug (my daughter’s dog) absolutely LOVES THIS TOY!
Size: 15 Inch
My daughters dog, Doug , loves this toy….. I have bought 3 of these in the past 12 months! Though he will destroy it, he chews and plays with it until there is almost nothing left!!!
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Reviewed in the United States on May 19, 2026

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