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Description
S100A8/MRP8 Recombinant Rabbit mAb (S-R251)Product Specification Host Rabbit Antigen S100A8 MRP8 Synonyms Calgranulin A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor related protein 8 (MRP 8; p8), S100 calcium binding protein A8, Urinary stone protein band A, CAGA Location Cytoplasm, Secreted, Cell membrane Accession P05109 Clone Number S R251 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu, Ms, Rt
Product Specification
| Host | Rabbit |
| Antigen | S100A8/MRP8 |
| Synonyms | Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8 (MRP-8; p8), S100 calcium-binding protein A8, Urinary stone protein band A, CAGA |
| Location | Cytoplasm, Secreted, Cell membrane |
| Accession | P05109 |
| Clone Number | S-R251 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:2000 | null |
Background
S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene. It is also known as calgranulin A. It is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis and post COVID-19 condition.
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