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Description
Phospho-IκBα (Ser32/36) Recombinant Rabbit mAb (S-751-40)Product Specification Host Rabbit Antigen Phospho IB (Ser32 36) Synonyms NF kappa B inhibitor alpha, I kappa B alpha (IkB alpha; IkappaBalpha), Major histocompatibility complex enhancer binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession P25963 Clone Number S 751 40 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Predicted Reactivity Ms, Pg, Pl Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | Phospho-IκBα (Ser32/36) |
| Synonyms | NF-kappa-B inhibitor alpha, I-kappa-B-alpha (IkB-alpha; IkappaBalpha), Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | P25963 |
| Clone Number | S-751-40 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Predicted Reactivity | Ms, Pg, Pl |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 |
Background
IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) is one member of a family of cellular proteins that function to inhibit the NF-κB transcription factor. IκBα inhibits NF-κB by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them sequestered in an inactive state in the cytoplasm. In addition, IκBα blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-κB's proper functioning.
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Exchange/Return Notes
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