SKU: 14432344175

Annexin A1 Recombinant Rabbit mAb(SDT-020-36)

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Description

Annexin A1 Recombinant Rabbit mAb(SDT-020-36)Product Specification Host Rabbit Antigen Annexin A1 Synonyms Calpactin II,ANX1, LPC1, Annexin I, Annexin 1, Calpactin 2, Chromobindin 9 Immunogen Recombinant Protein Accession P4083 Clone Number SDT 020 36 Antibody Type Rabbit mAb Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300

Product Specification


Host Rabbit
Antigen Annexin A1
Synonyms Calpactin II,ANX1, LPC1, Annexin I, Annexin-1, Calpactin-2, Chromobindin-9
Immunogen Recombinant Protein
Accession P4083
Clone Number SDT-020-36
Antibody Type Rabbit mAb
Application WB, IHC-P, ICC, ICFCM
Reactivity Hu, Ms, Rt
Purification Protein A
Concentration 0.5mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
IHC-P 1:2000 null
WB 1:1000 null
ICFCM 1:5000 null
ICC 1:500 null

Background

Annexin A1 belongs to the annexin family of Ca2+-dependent phospholipid-binding proteins that have a molecular weight of approximately 35,000 to 40,000 Dalton and are preferentially located on the cytosolic face of the plasma membrane. Annexin A1 protein has an apparent relative molecular mass of 40 kDa with phospholipase A2 inhibitory activity. In resting conditions, human and mouse immune cells such as neutrophils, monocytes, and macrophages contain high levels of annexin A1 in their cytoplasm. Following cell activation (for example, by neutrophil adhesion to endothelial-cell monolayers), annexin A1 is promptly mobilized to the cell surface and secreted. Annexin A1 promotes neutrophil detachment and apoptosis, and phagocytosis of apoptotic neutrophils by macrophages. On the other hand, it reduces the tendency of neutrophils to penetrate the endothelium of blood vessels. Higher expression of annexin A1 during pathological conditions could increase the strength of TCR signalling through the mitogen-activated protein kinase signalling pathway, thereby causing a state of hyperactivation of T cells.

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SKU: 14432344175

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4.5 ★★★★★
Based on 14 reviews
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B
Verified Purchase
BKossey929
Cuba, US
★★★★★ 5
This Pillow Is The Greatest!
Style: Standard - Tall
This pillow is amazing! It’s very pricey, but worth EVERY penny in both my opinion and my husband’s. My husband had been complaining about his old pillow for a while. I did some research and this pillow seemed to be the best of the best according to the reviews. But that price - yikes! I kept checking back and saw it was on sale and decided to take a chance. Bought it in the tall size (7.5 in.) and decided it would be his early birthday gift. The first night of him using it was AMAZING for both of us. He has snored like a freight train and will periodically stop breathing for 15-18 seconds throughout the night for the past 26 years that I know of. Immediately, his super loud snoring downgraded to a very low level of snoring. He said after the first night he fell asleep fast, did not wake up nearly as much and finally had no neck pain in the morning. He’s had it over a month now and says he can’t believe a pillow could make this big of a difference in his sleep quality. I can’t believe I don’t have to deal with his concert level snoring anymore. Plus, he no longer stops breathing for short intervals anymore! This pillow has been well worth the cost for us!
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Reviewed in the United States on April 2, 2026
D
Verified Purchase
Devin
Charlottesville, US
★★★★★ 5
Great pillow, my neck is grateful!
Style: Standard - Tall
I am a combination sleeper and this pillow is comfortable in almost any direction I lay. Definitely a relief on my neck compared to my previous cervical type pillows.
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Reviewed in the United States on May 17, 2026
W
Verified Purchase
Wilson07
New York, US
★★★★★ 4
Decent pillow; medium-firm; heavy
Style: King - Medium
I was looking to replace my old latex pillow from BBB. I have tried several but finding just the right one has been elusive. Although expensive, I was confident this would be THE one. Sadly, it isn't. For a latex pillow, this IS really nice. It is comfortable and solid latex - hard to find. It is medium-firm and has decent spring back. But for me, it doesn't have enough sink. It is actually too firm and I felt my neck was cranked all night (I am 5'6", 135#, side sleeper, ordered the 6.5" one). I do think the cooling Purple grid works pretty well but at the same time, I could feel the grid under my pillow case. The pillow is very heavy.
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Reviewed in the United States on February 26, 2026
B
Verified Purchase
Bean Burrito
Los Angeles, US
★★★★★ 1
It’s $30 to return and quickly STINKS from body heat
Style: Standard - Medium
Original review about $30 return below, but since it cost to return I gave it to my husband. He’s a hot sleeper so other than this pillow we’ve switched to all cotton, linen or wool bedding and it’s made a huge difference. (Polyester is plastic so it reflects your heat back to you and makes you sweat more and doesn’t breathe.) I truly would not have kept this pillow except $30 felt like a waste just to return and he got excited about it. So okay, it’s his. Well I’m the laundry queen in our household (he does all dishes) and I realized very quickly this pillow would need to be washed OFTEN. Like, once a week is NOT enough. Something about body heat and this material smells HORRIBLE. Washing it is obviously not easy, so I handwash the outer layer of the pillow with a very gentle soap (bought for silk). And then it has to hang dry. It doesn’t matter. I can clean it perfectly, no smell remaining whatsoever, but after two nights, it’s so strong I can smell it JUST STANDING NEAR THE BED. Look. I mentioned my hubs sleeps hot, sure. But he’s hygienic. This should not be such an issue. It’s never been an issue with any other pillows. The smell doesn’t even smell like him or like B.O. or anything. It’s awful and legitimately churns my stomach. But can I throw out the stupid $200 thing? Noooo. Now he’s attached. And I’m spending hours of my life each week washing it to keep from feeling sick sleeping near it at night. And to avoid having wasted $200. Hate this thing. DON’T BUY THIS STUPID PILLOW. Dropping from 2 stars to 1 Because of the smell. Original review: I thought I could buy this and see if the height would work for me. It didn’t, and pinched my neck instead. But now the *only* way to return it is to ship through UPS (not return to the UPS Store or Kohl’s or Whole Foods, which would be free). I was going to return it and try a different size, but such a high price just to *try* it is not worth it to me. I’ve returned much larger (defective) items in the past without hassle or cost (like an entire heavy duty garage shelf with broken pieces). Had I known, I would not have ordered in the first place, so I hope this saves someone else. As for the pillow itself, it was unique, but I couldn’t even really lay my head on it for more than a moment until I had let it air out for more than a week. It REEKED upon arrival. My husband said it smelled like ozone, and my brother compared it to the inside of an airplane. It burned my throat if I tried to lay on it for more than about 30 seconds at a time. Two and a half weeks later, the smell is still slightly there. So even if it was comfy for me, I would not keep this pillow.
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Reviewed in the United States on January 31, 2025
A
Verified Purchase
Adelina
Natrona Heights, US
★★★★★ 5
The best pillow for side and back sleeping
Style: King - Medium
Bought this pillow for my husband, he loves it. He is back sleeping and has been the best pillow so far. Worth the money. With buy one for me and my daughter. It’s a little pricey but when it comes to sleeping it’s worth the money.highly recommend
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Reviewed in the United States on May 13, 2026

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