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Description
Mouse CD4, His tagProduct Specification Species Mouse Synonyms T cell differentiation antigen L3T4, T cell surface antigen T4 Leu 3 Accession P06332 Amino Acid Sequence Protein sequence(P06332, Lys27 Thr394, with C 10*His)
Product Specification
| Species | Mouse |
| Synonyms | T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3 |
| Accession | P06332 |
| Amino Acid Sequence | Protein sequence(P06332, Lys27-Thr394, with C-10*His) KTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKEEVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSKVLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQSTAITAYKSEGESAEFSFPLNFAEENGWGELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDKGTLHQEVNLVVMKVAQLNNTLTCEVMGPTSPKMRLTLKQENQEARVSEEQKVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVNQTGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:42.9kDa Actual:53-60kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. The TCR complex and CD4 bind to distinct regions of the antigen-presenting MHC class II molecule. The extracellular D1 domain of CD4 binds to the β2 region of MHC class II. The resulting close proximity between the TCR complex and CD4 allows the tyrosine kinase Lck bound to the cytoplasmic tail of CD4 to phosphorylate tyrosine residues of immunoreceptor tyrosine activation motifs (ITAMs) on the cytoplasmic domains of CD3 to amplify the signal generated by the TCR.
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4.4 ★★★★★
Based on 30 reviews
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Product Reviews
★★★★★ 4
Can opener
It doesn't shut off by itself when done and doesn't shut off when I push the button, so after a while it will shut off but when it wants too after you take it off the can ,like 30 seconds. But I do like the way it cuts, a clean cut and lid removal nice.
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Reviewed in the United States on February 2, 2026
★★★★★ 5
terrible item
it worked a few times and it doesnt work at all! Terrible item!
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Reviewed in the United States on June 7, 2026
★★★★★ 1
Very dangerous metal shavings!!!
Negative stars if I could.
This is a very dangerous product. It worked well for a while. But then it quit effectively removing the lid instead I got little tiny shavings of metal around the edge. These shavings of metal go into the food and very dangerous.
So this was a waste of money and incredibly dangerous. I am throwing it in the trash today.
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Reviewed in the United States on March 25, 2026
★★★★★ 5
Practical and easy to use
This electric can opener performs its function well and gets the job done effortlessly. With just the press of a button, it opens cans quickly and smoothly—which is very useful, especially if you prefer not to exert physical force. The design is comfortable to handle and does not take up much space in the kitchen. The battery life is good, and it recharges without any issues. Overall, it is a functional product that makes an everyday chore much easier.
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Reviewed in the United States on April 20, 2026
★★★★★ 5
Works great
Ive broken so many manual can openers from sheer strength and this eliminates that issue not only because it no longer needs my input but because this device actually works! Would definitely recommend it. Usb c charging is a god send, no batteries!
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Reviewed in the United States on April 20, 2026
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