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Description
Alexa Fluor® 488 Mouse Anti-Human TCR γ/δ Antibody (S-R637)Product Specification Host Mouse Antigen TCR Synonyms T cell receptor ; TCR; TCR Location Cell membrane Accession P03986B7Z8K6 Clone Number S R637 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Mouse |
| Antigen | TCR γ/δ |
| Synonyms | T cell receptor γ/δ; γ/δ TCR; TCR-γ/δ |
| Location | Cell membrane |
| Accession | P03986、B7Z8K6 |
| Clone Number | S-R637 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
TCR γδ protein is a transmembrane disulfide-linked heterodimer composed of a γ and a δ chain, each containing a membrane-distal immunoglobulin-like variable (V) domain, a membrane-proximal constant (C) domain, a short stalk, a hydrophobic transmembrane anchor and a cytoplasmic tail that associates with CD3 and ζ signaling subunits; unlike conventional αβ T-cell receptors it recognizes native antigens—small pyrophosphate metabolites, lipids presented on MHC-like butyrophilin molecules, stress-induced MIC-A/B or even unprocessed surface proteins—without requiring peptide-MHC, triggering rapid innate-like cytokine and cytotoxic responses that bridge innate and adaptive immunity.
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Exchange/Return Notes
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