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Description
IL-23 Protein, RatProduct Specification Species Rat Synonyms IL 23 p19 IL 12 p40; IL23; IL 23A; Interleukin 23; SGRF Amino Acid Sequence IL 23alpha: VPRSSSPDWAQCQQLSRNLCTLAWSAHTPVGQMDLLREEGEEETKSDVPRIQCGDGCDPQGLKDNSQFCLQRIRQGLVFYKHLLDSDIFTGEPSLLPDSPVDQLHTSLLGLSQLLQPEDHHWETQQMPRLSPSQQWQRSLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA IL 12beta:
Product Specification
| Species | Rat |
| Synonyms | IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF |
| Amino Acid Sequence |
IL-23alpha: |
| Expression System | HEK293 |
| Molecular Weight |
Approximately 23(IL-23A) & 43-48 kDa((IL-12B))
|
| Purity | ＞90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer |
PBS, pH 7.4.
|
| Reconstitution |
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
|
| Stability & Storage |
Stored at -20°C for 2 years from date of receipt. |
Background
The IL-23 α protein is predicted to exhibit cytokine activity and contribute to interleukin-23 receptor binding. It is also anticipated to be involved in multiple processes, including the positive regulation of cytokine production, lymphocyte activation, and peptidyl-tyrosine phosphorylation. Additionally, it is expected to function upstream of T cell proliferation and in the positive regulation of RNA polymerase II transcription. This protein is localized in the extracellular space and is also predicted to be a component of the interleukin-23 complex. In terms of expression, it shows a bias toward the thymus (RPKM 15.2), spleen (RPKM 11.9), and nine other tissues. It shares orthology with the human *IL23A* gene, which encodes the interleukin-23 subunit alpha.
Components
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