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Description
CD94 Recombinant Rabbit mAb (S-2616-17)Product Specification Host Rabbit Antigen CD94 Synonyms Natural killer cells antigen CD94; KP43; Killer cell lectin like receptor subfamily D member 1; NK cell receptor; KLRD1 Immunogen Recombinant Protein Location Cell membrane Accession Q13241 Clone Number S 2616 17 Antibody Type Recombinant mAb Isotype IgG Application ICC, FCM Reactivity Hu Positive Sample NK 92, Human PBMC Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Antigen | CD94 |
| Synonyms | Natural killer cells antigen CD94; KP43; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor; KLRD1 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | Q13241 |
| Clone Number | S-2616-17 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | ICC, FCM |
| Reactivity | Hu |
| Positive Sample | NK-92, Human PBMC |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| ICC | 1:100 | Hu |
| FCM | 1:50 | Hu |
Background
CD94, encoded by KLRD1, is a type II transmembrane C-type lectin glycoprotein expressed predominantly on natural killer (NK) cells and subsets of CD8⁺ T cells, where it covalently assembles with NKG2A, C, E or F subunits to form disulfide-linked heterodimers that recognize the non-classical MHC-I molecule HLA-E (or Qa-1 in mice) and deliver either inhibitory or activating signals that finely tune cytotoxicity, cytokine secretion and survival of effector lymphocytes, thereby playing a central role in innate and adaptive immunity, tumor immune evasion, viral defense and pregnancy tolerance.
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Exchange/Return Notes
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