SKU: 1861932292

B7-H5/VISTA His Tag Protein, Human

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Description

B7-H5/VISTA His Tag Protein, HumanProduct Specification Species Human Accession AAH20568 Amino Acid Sequence Phe33 Ala194, with C terminal 8*His FKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQESENITAAGGGSHHHHHHHH Expression System HEK293 Molecular Weight 28 43 kDa(Reducing) Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance

Product Specification


Species Human
Accession AAH20568
Amino Acid Sequence

Phe33-Ala194, with C-terminal 8*His FKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQESENITAAGGGSHHHHHHHH

Expression System HEK293
Molecular Weight

28-43 kDa(Reducing)

Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1mg/mL according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Background

B7-H5, also known as VISTA, is one of the negative immune checkpoints of the B7 family. B7-H5 which is the most conserved among the B7 membersis mainly expressed in myeloid cells such as macrophages, monocytes, dendritic cells, and T cells VISTA is a type I transmembrane protein consisting of a single N-terminal immunoglobulin (Ig) V domain, an approximately 30 amino acid (aa) stalk, a transmembrane domain, and a 95 aa cytoplasmic tail. It can regulate a variety of immune cells, including B cells, T cells, and endothelial cells by binding to its putative receptor(s) on these cells. The expression of B7-H5 is closely related to the diagnosis, severity and prognosis of tumors.

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SKU: 1861932292

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4.6 ★★★★★
Based on 11 reviews
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Product Reviews
A
Amazon Customer
Bozeman, US
★★★★★ 5
Durable, Flavorful, Chew Toy
Size: Medium & Large, Color: Red Scorpion
This bacon flavored scorpion shaped dog toy has been a huge hit with my Labrador. The material feels extremely durable and appears to be made from a hard nylon that can stand up to serious chewing. At first, I was skeptical about the bacon scent because I couldn’t smell anything when I opened the package. The moment my dog started chewing on it, though, the bacon scent became much more noticeable. Anyone else who doesn’t smell it immediately shouldn’t worry because it definitely seems to activate once the toy gets some use. My dog is an enthusiastic chewer and has not been able to destroy this toy. Even better, I haven’t seen any meaningful signs of wear, gouging, or damage despite repeated chewing sessions. That level of durability is exactly what I was hoping for. The design also includes areas where treats can be added for extra enrichment, which adds even more value. Most importantly, it has seemed very safe during use, and I haven’t had to worry about pieces breaking off. Overall, this toy has been durable, engaging, and well worth it. My dog loves it, and I love having a chew toy that can actually survive more than a few days.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 5, 2026
J
John
Lake Worth, US
★★★★★ 5
Built Tough Enough to Handle Serious Chewers
Size: Medium & Large, Color: Red Scorpion
This toy is noticeably harder and denser than standard dog chew toys, which is the whole point. My dog went after it immediately and the nylon held up through serious chewing sessions without gouging, cracking, or pieces breaking off. For a dog that destroys softer toys in minutes, this actually lasts. Based on a few weeks of use I would expect it to hold up for a month or longer depending on the dog, which is significantly better than most toys in this price range. The peanut butter groove is the engagement feature that makes a difference. Stuffing it with peanut butter or other spreadable treats keeps a dog interested longer than just chewing on it plain. The scorpion shape (though it resembles a lobster to some eyes) gives multiple parts to chew on, so the dog can rotate between the legs and tail when one section gets boring. That variety helps extend how long the toy stays interesting. Cleanup is straightforward since it is dishwasher safe, which matters after using peanut butter or other treats in the groove. The teeth cleaning claim is harder to verify in short-term use, but as a durable boredom relief toy for aggressive chewers this performs solidly. It is the kind of toy that actually justifies the price because it does not end up in the trash after a week.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 30, 2026
A
Amazon Customer
Draper, US
★★★★★ 5
Crawfish that cleans her teeth and tastes like bacon, enough said.
Size: Medium & Large, Color: Red Scorpion, Size: Medium & Large, Color: Red Scorpion
This chew toy is for a medium to large-sized dog and smells like bacon, and who doesn't love bacon? The toy has a heavy-duty safe for dogs nylon core, making it virtually indestructible for aggressive, all-day chewers like my dog. I am from Louisiana, and I love all things crawfish. I thought if she didn't like it, then I could use it to decorate for crawfish parties, but she loves this toy. There is a groove for treats like peanut butter or cheese, whatever your dog is into. My dog likes carrying it around, but I don't think she understands to chew on it yet. However, she must love the bacon taste in her mouth because she hardly takes it out. I wanted her to chew on it to help clean her teeth; maybe in time, she will start. This toy is dishwasher safe after rinsing it off with soapy warm water. Just place it on the top rack and turn it on. The crawfish is smooth and non-porous, so there are no spots for bacteria to hide. I really like this crawfish, and I hope that in time my little weirdo will understand that it is meant to be chewed, not sucked on. I highly recommend this for larger dogs that love to chew, and I am happy with this order.
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Reviewed in the United States on May 29, 2026
J
Joe’s Garage
Pawtucket, US
★★★★★ 1
Our dogs wouldn’t touch this chew toy
Size: Medium & Large, Color: Red Scorpion, Size: Medium & Large, Color: Red Scorpion
I ordered this Bacon Flavored Nylon Chew Toy for my boxer mix dog. She sniffed it and wouldn’t have anything to do with it. We waited a day and still no luck. We figured that we would give it to our pit bull because she can annihilate a chew toy. Nope, she wouldn’t touch it. The thing looks like a big chunk of plastic with a very faint smell of bacon. Based on our experience with this product I cannot recommend it.
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Reviewed in the United States on June 9, 2026
K
KandS
Omaha, US
★★★★★ 5
Surprisingly Tough Chew Toy for Aggressive Chewers
Size: Medium & Large, Color: Red Scorpion, Size: Medium & Large, Color: Red Scorpion
This chew toy is made from a very hard nylon style material and feels substantially tougher than the average dog toy. It definitely seems geared toward aggressive chewers and larger dogs that destroy softer toys quickly. Our pup immediately liked it, especially with the peanut butter groove feature, which helped keep them interested longer. The toy feels almost indestructible during normal chewing sessions and has held up very well so far with no major gouges, cracks, or chunks coming off. Based on first impressions, I would expect this to last at least a month or more for many dogs, which is far better than a lot of chew toys in this price range. Another nice bonus is that it is dishwasher safe, making cleanup easy after using peanut butter or other treats in the groove. As for the teeth cleaning claim, I honestly cannot comment much on that yet. I have not personally noticed any obvious difference in our dog’s teeth or dental condition from using it. Still, as a durable boredom relief chew toy for aggressive chewers, it has been a solid performer so far and seems like a good value.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026

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