SKU: 20837645085

Cardiac Troponins I (cTnI) His Tag, Human

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Description

Cardiac Troponins I (cTnI) His Tag, HumanProduct Specification Species Human Synonyms cardiac troponin I,Human Cardiac Troponin I; cardiac troponin I,Human Cardiac Troponin I Accession P19429 Amino Acid Sequence MHHHHHHDDDDKADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES. Expression System E. coli Molecular Weight 28 kDa Purity 95%,

Product Specification


Species Human
Synonyms cardiac troponin-I,Human Cardiac Troponin I;cardiac troponin-I,Human Cardiac Troponin I
Accession P19429
Amino Acid Sequence MHHHHHHDDDDKADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES.
Expression System E.coli
Molecular Weight 28 kDa
Purity >95%, by SDS-PAGE under reducing conditions
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 1mM DTT, 2M Urea, pH8.0
Reconstitution Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability & Storage

· 12 months from date of receipt, -20 to -70 °C as supplied. 
· 6 months, -20 to -70 °C under sterile conditions after reconstitution.
· 1 week, 2 to 8 °C under sterile conditions after reconstitution.  
· Please avoid repeated freeze-thaw cycles.

Background

Cardiac Troponins I (cTnI), the Chinese name cardiac troponin I subunit, and cardiac troponin T subunit and cardiac troponin C subunit constitute cardiac troponin complex. Cardiac troponin complex is a calcium regulatory protein, which is used to regulate the contractile function of skeletal muscle and myocardium. When the concentration of intracellular Ca2+ is low, cTnI subunit can inhibit the interaction between troponin and troponin, and then inhibit the formation of myofibrinin. At present, cTnI is only found in cardiomyocytes and is released into the bloodstream after myocardial injury. Therefore, cTnI has high myocardial specificity and sensitivity, and is an important biomarker in the early diagnosis of acute myocardial infarction.

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SKU: 20837645085

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