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Description
ROR2 His Tag Protein, HumanProduct Specification Species Human Synonyms ROR2, NTRKR2, Receptor Tyrosine Kinase Like Orphan Receptor 2, BDB1 Accession A1L4F5 Amino Acid Sequence Glu34 Gly403, with C terminal 8*His
Product Specification
| Species | Human |
| Synonyms | ROR2, NTRKR2, Receptor Tyrosine Kinase Like Orphan Receptor 2, BDB1 |
| Accession | A1L4F5 |
| Amino Acid Sequence | Glu34-Gly403, with C-terminal 8*His EVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVPSCSPRDSSKMGGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 50-60kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Liu Y. et al. (2007) Homodimerization of Ror2 tyrosine kinase receptor induces 14-3-3(beta) phosphorylation and promotes osteoblast differentiation and bone formation. Mol Endocrinol. 21: 3050-3061. 2、Afzal A R. et al. (2000) Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2. Nat Genet. 25: 419-422. 3、van Bokhoven H. et al. (2000) Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome. Nat Genet. 25: 423-426. |
Background
Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is broadly expressed during embryonic development and can be found in cells of all three germ layers as well as in most organ tissues. ROR2 binds the Wnt family ligand, Wnt-5a, to activate non-canonical Wnt signaling pathways. Activation of ROR2 signaling promotes cellular proliferation, differentiation, cell-polarization, and migration. ROR2 is important for osteogenic and chondrogenic differentiation of mesenchymal stem cells. ROR2 is also involved in neurite outgrowth and synapse development in the brain.
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4.1 ★★★★★
Based on 28 reviews
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Product Reviews
★★★★★ 3
Nice small wallet, almost too small, ID pocket not very useful
Color: Two Tone - Cobalt Blue
It looks really nice and well-made, but the ID windowed pocket is too tight to easily get out your ID then you need to use it. No one lets you keep your ID in the wallet, so why bother with a clear window pocket?
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Reviewed in the United States on April 10, 2025
★★★★★ 5
A beauty!
Size: One Size, Color: Brown, Black
Oooo lala! I love it! Beautiful color. Well made and just the right size.
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Reviewed in the United States on March 3, 2026
★★★★★ 5
Lots of Space for a Small Bag
Colorful and great! All
Haven't been without a Coach bag since the early 1970s. I'm usually not fond of the signature bags, but this one is striking. Of course it is well made.
The bag has two compartments that are large enough for checkbook & phone. It has 8 card holders, 2 smaller places for business & library cards, a place for folding money, a zipper middle compartment and 3 flat compartments for receipts, notes, etc that are all packed into a cool small bag. It comes with both a crossbody metal strap and a leather wrist strap.dd
Often, I've found Coach credit card holders inside their bags are too small for credit cards. This bag has larger cardholders. Overall, I give it an A+.
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Reviewed in the United States on June 3, 2025
★★★★★ 5
10/10
Size: One Size, Color: Brown, Black
I bought it as a gift, and it’s perfect! The design is classy, the leather feels premium, and it goes with everything. Great size and amazing quality as always.
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Reviewed in the United States on November 7, 2025
★★★★★ 5
Great purchase
Lovely.. this bag met all my expectations and more
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Reviewed in the United States on May 19, 2026