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Description
Alexa Fluor® 647 Rat Anti-Mouse CD252 Antibody (S-R735)Product Specification Host Rat Antigen CD252 Synonyms Tumor necrosis factor ligand superfamily member 4; OX40 ligand (OX40L); Ox40l; Txgp1l; Tnfsf4 Location Membrane Accession P43488 Clone Number S R735 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample stimulated mouse splenocytes B cells Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA,
Product Specification
| Host | Rat |
| Antigen | CD252 |
| Synonyms | Tumor necrosis factor ligand superfamily member 4; OX40 ligand (OX40L); Ox40l; Txgp1l; Tnfsf4 |
| Location | Membrane |
| Accession | P43488 |
| Clone Number | S-R735 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | stimulated mouse splenocytes B cells |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Ms |
Background
CD252, also known as OX40 ligand (OX40L), is a membrane-bound cytokine of the tumor necrosis factor superfamily expressed on activated antigen-presenting cells that engages its receptor OX40 (CD134) on T cells to deliver a potent costimulatory signal driving T-cell proliferation, survival and effector cytokine production while also participating in B-cell/T-cell cross-talk and being exploited as a therapeutic target in cancer immunotherapy and autoimmune disease modulation.
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