SKU: 23796637647

CD44 Mouse mAb (Alexa Fluor® 488 Conjugate) (S-630-174)

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Description

CD44 Mouse mAb (Alexa Fluor® 488 Conjugate) (S-630-174)Product Specification Host Mouse Antigen CD44 Synonyms CDw44, Epican, Extracellular matrix receptor III (ECMR III), GP90 lymphocyte homing adhesion receptor, HUTCH I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1 (PGP 1), Phagocytic glycoprotein I (PGP I), LHR, MDU2, MDU3, MIC4 Immunogen Recombinant Protein Location Cell membrane Accession P16070 Clone Number S 630 174 Antibody Type Mouse mAb Isotype

Product Specification


Host Mouse
Antigen CD44
Synonyms CDw44, Epican, Extracellular matrix receptor III (ECMR-III), GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1 (PGP-1), Phagocytic glycoprotein I (PGP-I), LHR, MDU2, MDU3, MIC4
Immunogen Recombinant Protein
Location Cell membrane
Accession P16070
Clone Number S-630-174
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM, IF
Reactivity Hu
Purification Protein G
Concentration 2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer PBS, 0.1% BSA, 0.01% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:2000
IF 1:200

Background

The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. It participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44, along with CD25, is used to track early T cell development in the thymus. CD44 expression is an indicative marker for effector-memory T-cells. Memory cell proliferation (activation) can also be assayed in vitro with CFSE chemical tagging. In addition, variations in CD44 are reported as cell surface markers for some breast and prostate cancer stem cells. In breast cancer research CD44+/CD24- expression is commonly used as a marker for breast CSCs and is used to sort breast cancer cells into a population enriched in cells with stem-like characteristics and has been seen as an indicator of increased survival time in epithelial ovarian cancer patients.

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Exchange/Return Notes
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SKU: 23796637647

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4.5 ★★★★★
Based on 7 reviews
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Product Reviews
C
Verified Purchase
CoCo
Natrona Heights, US
★★★★★ 3
Too Hard
Color: Blue T-Bone, Size: 1 Count
I have a pit puppy, 20 lbs, who loves to chew. She's huge for her age, and I wanted to get her a new toy. I bought two different toys, hoping she would like one. The other toy was a hit, they both jumped at it and were excited about it, probably because it had rawhide rings that went with it. This one was immediately thrown to the side, even though my pit loves to chew on non edible toys. I think this one was just too hard, because both her, and my Chihuahua-Jack Russell, weren't interested. It didn't have any smell to attract them, which is why I bought it, because they love peanut butter stuff. I'm not going to go as far as to lick it and taste it... I'm pretty sure it won't taste like peanut butter, either. I feel so bad for my little pittie, she's just sitting here with a sad look on her face because my other dog stole the fun chew toy. I've immediately ordered another of one of those so they both have one, but I've just money wasted on this one. It's probably better they don't like it, I'd be worried about them breaking their teeth. I know it's supposed to be for power chewers, but it has no give whatsoever, just extremely hard, shiny plastic. It's useless, unless you're planning on filing it into a point and making a prison shank. Maybe you can leave it in front of the fridge for your SO to step on in the middle of the night when he goes to steal your almond milk. I'll figure out some way to use it. I did dip it into my boyfriend's peanut butter jar to let my puppy lick it, but I can do that with a spoon. I wanted her to feel like she got something, maybe my other dog will let her have a turn with the fun toy after awhile. That's the only reason I gave it 3 stars. You can dip it in peanut butter and I was being generous.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 27, 2022
R
Verified Purchase
Robert D Fry
Port Orchard, US
★★★★★ 5
Can become brittle with sharp edges with use.
Color: Blue T-Bone, Size: 1 Count
Our little dog loved chewing this, however after chewing the toy became jagged and brittle with sharp edges that cut into her upper lip which took about 2 weeks to heal. Unfortunately the return window had closed.
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Reviewed in the United States on March 10, 2026
A
Verified Purchase
Amy Bagby
San Leandro, US
★★★★★ 5
Busy bone
Color: Blue T-Bone, Size: 1 Count, Color: Blue T-Bone, Size: 1 Count
My dog loves these!! Great busy bone! And they can hold it with her paws really well. It does kill your foot if you step on it barefoot in the middle of the night. This is a picture of the bone after 7months.
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Reviewed in the United States on June 1, 2026
A
Verified Purchase
Arleen K. Olson
Los Angeles, US
★★★★★ 5
My Dog Loves this!
Color: Blue T-Bone, Size: 1 Count, Color: Blue T-Bone, Size: 1 Count
My dog loves her Nubbies! My Dog chews her Nubbie every morning after she has her breakfast. She sometimes wants my husband or I to hold it for her while she chews on it. I think it is really good for her teeth and gums. These last a few months for our dog who chews it every morning. After a few months the edges get a little rough from all the chewing so I throw it out and replace with a new one. These are very reasonably priced, so I always have a fresh one ready to go. She gets very excited when we get a new one out of the package..
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Reviewed in the United States on September 5, 2025
J
Verified Purchase
Jamie Liverseed
Massapequa, US
★★★★★ 5
Very durable!
Color: Blue T-Bone, Size: 1 Count
Great product! Dogs love it and very durable. I had been buying the nylon bones in pack of 3, but my 2 dogs would chew them up in no time, and I was buying the aggressive chewer bones. Bought 2 of these, dogs loved it, so I bought another one. Have had these for about 2- 2 1/2 months and still holding up just fine. And the price is great! Would definitely recommend!
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Reviewed in the United States on May 5, 2026

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