SKU: 2503364479

IL-28B/IFNL3 Protein, Mouse

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Description

IL-28B/IFNL3 Protein, MouseProduct Specification Species Mouse Synonyms IL 21B,IFNL3 Accession Q8CGK6 Amino Acid Sequence Asp20 Val193 Expression System E. coli Molecular Weight 20kDa (Reducing) Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation. Stability & Storage 12

Product Specification


Species Mouse
Synonyms IL-21B,IFNL3
Accession Q8CGK6
Amino Acid Sequence Asp20-Val193
Expression System E.coli
Molecular Weight

20kDa (Reducing)

Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Sci Rep. 2020 Dec 1;10(1):20973. 

2. Int Immunopharmacol. 2022 Aug:109:108799.  Epub 2022 May 4.

Background

IL-28 is a family of cytokines that belongs to interferons termed as λ-interferons or type III interferons (IFN). This family includes IL-28A(IFN-λ2), IL-28B(IFN-λ3) and IL-29(IFN-λ1) in human and IL-28A and IL-28B in mice. IL-28A, IL-28B and IL-29 share a unique heterodimeric receptor IFNLR consisting of IL-28Rα and IL-10R, which is mainly expressed by epithelial cells, dendritic cells (DCs) and macrophages. IL-28B inhibits M2 macrophage polarization in vitro, while also halting M2 macrophage differentiation predominantly via inhibition of the signal transducer and activator of transcription (STAT)3 and c-Jun N-terminal kinase (JNK) signaling pathways. Results reveal a protective role of IL-28B via regulation of epithelial cells in protease induced asthma.

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SKU: 2503364479

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jd
Charlottesville, US
★★★★★ 5
Perfect fit for my fit
Size: 2" x 10" x 11"
Bought this for my Honda fit sport. Perfect fit for my fit. We shall see how it works out in the long run. I'm guessing every six months I'll wash it out, give it a light piling with the refresher kit I bought. The car doesn't get driven a lot during the year, so, doing it this way should be more than fine.
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Reviewed in the United States on April 22, 2026
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P Patel
Waukegan, US
★★★★★ 5
Premium, Reusable Cabin Filter – Worth It Long-Term
Size: 2" x 10" x 11"
I've been using the K&N Lifetime Washable Cabin Air Filter in my vehicle for several months, and here's my experience: Pros: Washable & Reusable: Eliminates the need for frequent replacements, saving money over time. Improved Airflow: Noticed a slight increase in airflow through the vents, enhancing cabin comfort. Odor Control: Effectively reduces musty smells, providing a fresher cabin environment. Cons: Initial Cost: Priced higher than disposable filters, but the long-term savings offset this. Cleaning Required: Needs periodic cleaning to maintain performance, which might be inconvenient for some users.
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Reviewed in the United States on June 25, 2025
A
Verified Purchase
Alan Douglas Charles Cavanaugh II
Pawtucket, US
★★★★★ 5
Must have over other filters.
Size: 2" x 10" x 11"
Amazing KN never fails for cabin filter works great in my 2021 Honda Civic hatchback sport touring.Must have for the 10th Gen Civic better air flow in car and cleaner smell easy to wash and reuse.
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Reviewed in the United States on April 25, 2026
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Martha Brown
Grantham, US
★★★★★ 5
Quality
Size: 2" x 10" x 11"
My brother put me onto these filters. Super easy to install. Also bought engine filter. One time expense. A bit pricey but cost covered if you were still buying paper ones in about 3 changes of paper ones. Will definitely pay for themselves. Highly recommend
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Reviewed in the United States on March 18, 2026
J
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James G. Low
Alexandria, US
★★★★★ 5
It works like a champ!!
Size: 2" x 10" x 11"
best darn filter made..
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Reviewed in the United States on April 10, 2026

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