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Description
S-RMab® alpha smooth muscle Actin (SMA) Recombinant Rabbit mAb (SDT-301-142)Product Specification Host Rabbit Antigen alpha smooth muscle Actin (SMA) Synonyms Alpha actin 2, ACTA2, Smooth muscle actin, actin sm, ASM 1, CGA7, ASM H12 Immunogen Synthetic Peptide Location Cytoplasm, Cytoskeleton Accession P62736 Clone Number SDT 301 142 Application WB, IHC P, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 25 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | alpha smooth muscle Actin (SMA) |
| Synonyms | Alpha-actin-2, ACTA2, Smooth muscle actin, actin-sm, ASM-1, CGA7, ASM/H12 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cytoskeleton |
| Accession | P62736 |
| Clone Number | SDT-301-142 |
| Application | WB, IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:1000 | |
| IF | 1:500 |
Background
Alpha smooth muscle actin, encoded by ACTA2, is expressed in abundance in vascular smooth muscle, comprising 50–70% of total actin, with the remainder composed of β-cytoplasmic and γ-actins. Whereas α-smooth muscle expression is normally restricted to smooth muscle cells, it can also be expressed in non-muscle cells, most notably myofibroblasts that use cell traction forces to remodel extracellular matrix.
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Exchange/Return Notes
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