SKU: 28328197979

PE-Cy7 Armenian hamster Anti-Mouse/Rat/Human CD27 Antibody (S-R620)

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Description

PE-Cy7 Armenian hamster Anti-Mouse/Rat/Human CD27 Antibody (S-R620)Product Specification Host Armenian hamster Antigen CD27 Synonyms CD27 antigen; CD27L receptor; T cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7Imported; TNFRSF7 Location Cell membrane Accession P26842P41272Q501W2 Clone Number S R620 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Hu, Ms, Rt Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation PE Cy7

Product Specification


Host Armenian hamster
Antigen CD27
Synonyms CD27 antigen; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7Imported; TNFRSF7
Location Cell membrane
Accession P26842、P41272、Q501W2
Clone Number S-R620
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Hu, Ms, Rt
Positive Sample Human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation PE-Cy7
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu, Ms, Rt

Background

CD27 protein is a member of the tumor necrosis factor (TNF) receptor superfamily. It is expressed on the surface of various immune cells such as T cells and B cells. CD27 can interact with its ligand CD70, which is mainly found on antigen - presenting cells (APCs) and activated T cells. This interaction plays a crucial role in the regulation of immune responses. It can promote T cell proliferation and differentiation, enhance the cytotoxic activity of T cells against infected or cancerous cells, and also participate in the regulation of B cell functions such as immunoglobulin production. Moreover, the CD27 - CD70 pathway is involved in the development and maintenance of immune memory, helping the immune system to remember and respond more effectively to pathogens it has previously encountered. Abnormal expression or function of CD27 has been implicated in certain immune - related diseases and cancers, making it a potential target for therapeutic interventions in these conditions.

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SKU: 28328197979

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Dr. Earl C. Johnson
Waukegan, US
★★★★★ 4
Enjoyed reading some of the best poems ever written. Took me places I’ve never been.
Format: Paperback
Some of the poems were difficult to comprehend and may require a re-reading to understand their full meaning. But that is the brilliance of G. Brooks, putting you in places of the mind that one has never been. Won’t recommend for newbies!
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Reviewed in the United States on September 10, 2021
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Kymberlyn A Reed (The Fountain Pen Diva)
Fort Morgan, US
★★★★★ 4
A Great Historical Noir
Format: Kindle
As a lifelong Angeleno, the dark history of the city is often glossed over. Much like Chavez Ravine, the history of Union Station is one of violence and the forced displacement of the original Chinatown and its residents. It's in this setting where the mysterious death of Chinese actress Lulu Wong (who is somewhat based on the real life of actress Anna Mae Wong) begins, and took me into the lives of the amazing Chow sisters - May and Gemma - both of whom have their own reasons for wanting justice. They know the LA cops won't bother to solve the death of a Chinese woman, no matter how famous. It's also a matter of saving their beloved Chinatown from being destroyed in order to build Union Station. I absolutely loved how immersive this story felt and how authentic all of the characters were.
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Reviewed in the United States on June 17, 2024
S
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Sandy Worchester
Phoenix, US
★★★★★ 5
noir
Format: Kindle
Always the last person you can think of is the murderer. The same with this book also. I love learning about new cultures and you can learn some things about Chinese culture from this book. So interesting
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Reviewed in the United States on September 6, 2024
H
Heather Harrington
Fort Morgan, US
★★★★★ 3
Pretty good
Format: Hardcover
In 1932, Lulu Wong made a name for herself by leaving Chinatown and becoming a Hollywood star. Most girls who look like her don't get lead roles, so Lulu is the pride of her neighborhood. So everyone is shocked when Lulu's body is found in a local stable far from her Beverly Hills home by her friends, sisters May and Gemma. The girls know that the police won't look too hard into the murder, so they decide to take matters into their own hands. As they investigate, the sisters discover a plot to frame Chinatown as a den of iniquity that should be demolished in favor of constructing a new train station. May and Gemma soon find themselves in a race against time to not only find justice for their friend but save their neighborhood, all while being targeted by a killer. I've only read a few books by Lee, but they've all been winners. I love her style when it comes to YA historical fiction. She crafts compelling plotlines that include real issues of the time with characters you can't help but root for. I liked both our main characters. May was more logical and reserved, while Gemma was a spitfire, but they balanced each other perfectly. I liked how we got both of their POVs, but I did enjoy Gemma's slightly more because I loved her gumption. I thought the mystery was well-paced and kept me intrigued. I had no clue how it would play out, and I liked how Lee wrapped it all up. It did drag a bit in the middle, but overall, I thought it was entertaining.
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Reviewed in the United States on April 23, 2024
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J. Kuntze
Grantham, US
★★★★★ 4
not as good but nearly there
Format: Kindle
I had hoped that Kill Her Twice would grab my attention in the first few pages and not let go till the very end (like her other books I have read), but this one had a very. Slow. Start. The mystery of the death of a young Chinese starlet in California in the early 1900’s is the catalyst that starts everything: new characters are continuously introduced, their motivations becoming clear and murky and clear again several times before the last quarter of the book. But. The last quarter (finally) had me hooked.
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Reviewed in the United States on January 1, 2025

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