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Description
Rat Anti-Mouse Ki67 Antibody (S-R595)Product Specification Host Rat Antigen Ki67 Synonyms Proliferation marker protein Ki 67; Antigen identified by monoclonal antibody Ki 67 homolog (Antigen KI 67 homolog; Antigen Ki67 homolog); Mki67 Location Nucleus Accession E9PVX6 Clone Number S R595 Antibody Type Rat mAb Isotype IgG2a,k Application ICFCM Reactivity Ms Positive Sample NIH 3T3 Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rat |
| Antigen | Ki67 |
| Synonyms | Proliferation marker protein Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog (Antigen KI-67 homolog; Antigen Ki67 homolog); Mki67 |
| Location | Nucleus |
| Accession | E9PVX6 |
| Clone Number | S-R595 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | ICFCM |
| Reactivity | Ms |
| Positive Sample | NIH/3T3 |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICFCM | 1:200 | Ms |
Background
Ki67 protein is a non-histone nuclear protein encoded by the MKI67 gene, widely used as a proliferation marker in pathology. It is expressed during all active phases of the cell cycle—G1, S, G2, and M—but is absent in quiescent (G0) cells. Ki67 has multiple molecular functions, including forming the perichromosomal layer to prevent chromosome aggregation during mitosis and organizing heterochromatin. It also facilitates chromosome attachment to the mitotic spindle and individual chromosome mobility. In addition to its role in cell division, Ki67 is a valuable prognostic and predictive indicator in cancer diagnosis, with its expression levels correlating with tumor cell proliferation rates.
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4.6 ★★★★★
Based on 6 reviews
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Product Reviews
★★★★★ 5
Labs love this!!!
Style: Sport, Size: Large
Our Lab LOVES everything about this thing! Recommend getting extra durable balls as the 1 included fell apart in 1 hour. I have a very energetic Lab retriever that we have to force to stop playing ball so he does not overheat. That & the force with which you can throw this ball did not help keeping it from splitting it in 2 in less than 1 hour.
This is worth the money for the extra throwing power & distance but do invest in the ULTRA strong ball for dogs like retrievers! Also, be sure to order the correct SIZE OF BALL, specific to each different size of throwing wand.
My fav thing about this item is #1 the joy my dog gets from the new challenge of racing to catch longer throws, & #2 I don't have to get my hands covered in dog slobber!!
He has gotten to where he can almost put it in the cup himself so I won't waste time throwing the ball again!
Man, I love that dog!!! ❤️
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Reviewed in the United States on November 1, 2023
★★★★★ 5
Must-Have for Active Dogs!
Style: Sport, Size: Large
The Chuckit Sport 26L Dog Ball Launcher has been a game-changer for my large dog! My 80-pound Labrador loves to play fetch, and this launcher makes it so much easier and more enjoyable for both of us.
The 26” length gives me the leverage to throw the ball much farther than I could by hand, which really helps burn off my dog’s energy. The included large ball (3”) is the perfect size for big dogs, and I appreciate that it’s made from durable rubber, so it withstands a lot of chewing and rough play.
What I really love is that the launcher is so lightweight and easy to use. I can play fetch with my dog for extended periods without my arm getting tired. The ergonomic handle also provides a comfortable grip, which is a nice touch.
If you have a large, active dog, the Chuckit Sport 26L is a must-have. It’s well-made, durable, and makes fetch more fun for both you and your dog. Highly recommend!
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Reviewed in the United States on September 3, 2024
★★★★★ 5
ChuckIt is AMAZING!
Style: Sport, Size: Large
I can't throw a ball to save my soul. Just got this today and lobbed a ball to the far end of my 1- acre yard. The dog loves it, and I love it!
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Reviewed in the United States on March 8, 2026
★★★★★ 4
I recommend using the KONG Extreme Dog Toy
Style: Sport, Size: Large
Helpful for throwing as much as my dog wants to fetch. I actually had to get a cortisone injection in my shoulder a few months after getting my dog - never had a dog with this much energy before! The Chuckit really helps.
Downside: The ball that comes with it is larger than a tennis ball, so may be too much for smaller doge. I can't imagine my sister-in-law's french bulldog carrying it! Also, in our house it gets destroyed within minutes, as my dog is a strong chewer. For this situation, I recommend using the KONG Extreme Dog Toy, Black, size Large.
This is shaped sort of like a snowman, which means it bounces unpredictably at times. My dog eventually chews the "head" off of this toy, but the remaining 2/3 still fits in the Chuckit (and is actually easier to throw with the "head" missing!). One caveat: the KONG is significantly heavier than the ball included with the Chuckit, so be aware of that...
Also, we ordered our first Chickit in October 2015, then needed to replace it in May of 2017, as it broke. I think the plastic became brittle over that time, as we left it out in the sun & rain in Florida. Since it is cheap to replace, that's not a big deal. (We ordered three Kong toys over that same period of time!)
To summarize, it's a very helpful tool to get the ball further, faster, with less strain, than without it. Knowing there are alternatives to the included ball for heavy chewers makes it worthwhile.
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Reviewed in the United States on July 19, 2017
★★★★★ 5
Great Ball Launcher!
Style: Sport, Size: Large
Our dogs love this ball launcher! I can throw the ball long distances without any arm strain. The balls wear out, and as described by others, tennis balls don’t fit. Buy extra balls if this is of concern. We bought a few of the “Chuck It” rubber 3” balls and they have worked well for our dogs. It’s a great value and fun for the dogs.
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Reviewed in the United States on March 28, 2025