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Description
Amyloid Precursor Protein Recombinant Rabbit mAb (S-806-13)Product Specification Host Rabbit Synonyms APP, ABPP, APPI, Alzheimer disease amyloid A4 protein homolog, Alzheimer disease amyloid protein, Amyloid beta precursor protein, Amyloid beta (A4) precursor protein, Amyloid beta A4 protein, Cerebral vascular amyloid peptide (CVAP), PreA4, Protease nexin II (PN II) Immunogen Synthetic Peptide Location Cell membrane Accession P05067 Clone Number S 806 13 Antibody Type Recombinant mAb Isotype IgG Application
Product Specification
| Host | Rabbit |
| Synonyms | APP, ABPP, APPI, Alzheimer disease amyloid A4 protein homolog, Alzheimer disease amyloid protein, Amyloid-beta precursor protein, Amyloid-beta (A4) precursor protein, Amyloid-beta A4 protein, Cerebral vascular amyloid peptide (CVAP), PreA4, Protease nexin-II (PN-II) |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P05067 |
| Clone Number | S-806-13 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu |
| Predicted Reactivity | Fs, Pg, Ms, Rt, Mq, Cz, GP, Pr |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:100 | |
| ICC | 1:100 | |
| ICFCM | 1:500 |
Background
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor and has been implicated as a regulator of synapse formation, neural plasticity, antimicrobial activity, and iron export. APP is best known as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.
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