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Description
TAS2R14 Recombinant Rabbit mAb (S-1974-10)Product Specification Host Rabbit Antigen TAS2R14 Synonyms Taste receptor type 2 member 14; T2R14; Taste receptor family B member 1 (TRB1) Immunogen Synthetic Peptide Location Membrane Accession Q9NYV8 Clone Number S 1974 10 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample MCF7, TT Predicted Reactivity Cz Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | TAS2R14 |
| Synonyms | Taste receptor type 2 member 14; T2R14; Taste receptor family B member 1 (TRB1) |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | Q9NYV8 |
| Clone Number | S-1974-10 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | MCF7, TT |
| Predicted Reactivity | Cz |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
Background
TAS2R14, also known as taste receptor type 2 member 14, is a protein encoded by the TAS2R14 gene in humans and belongs to the G-protein-coupled receptor superfamily. It is specifically expressed in the taste receptor cells of the tongue and palate epithelia and is genetically linked to loci that influence bitter perception. This receptor is notable for its ability to recognize a wide range of chemically diverse bitter substances, making it one of the most broadly tuned bitter taste receptors. In addition to its role in taste perception, TAS2R14 is expressed in various non-gustatory tissues, such as human airway smooth muscle, where it has been shown to mediate bronchodilation and produce bactericidal levels of nitric oxide, suggesting potential therapeutic applications for respiratory diseases. Recent studies have also revealed its involvement in immune defense mechanisms and its potential as a target for host-directed therapies.
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