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Description
CEBP Beta (C-terminal) Recombinant Rabbit mAb (S-773-48)Product Specification Host Rabbit Synonyms CCAAT enhancer binding protein beta, C EBP beta, Liver activator protein (LAP), Liver enriched inhibitory protein (LIP), Nuclear factor NF IL6, Transcription factor 5 (TCF 5), CEBPB, TCF5 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession P17676 Clone Number S 773 48 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration
Product Specification
| Host | Rabbit |
| Synonyms | CCAAT/enhancer-binding protein beta, C/EBP beta, Liver activator protein (LAP), Liver-enriched inhibitory protein (LIP), Nuclear factor NF-IL6, Transcription factor 5 (TCF-5), CEBPB, TCF5 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | P17676 |
| Clone Number | S-773-48 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| ICC | 1:500 | |
| ICFCM | 1:500 |
Background
CEBP beta is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. It is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, CEBP beta can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
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