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Description
Biotinylated CD3E&CD3D Fc, His, Avi tag&Fc, Flag, Avi tag Heterodimer Protein, HumanProduct Specification Species Human Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D, CD3 delta & CD3 epsilon Accession P07766 1P04234 1 Amino Acid Sequence Asp 23 Asp 126 (CD3E) with hIgG1 Fc Tag at the C Terminus, followed by polyhistidine tag and Avi tag Phe 22 Ala 105 (CD3D) with hIgG1 Fc Tag at the C Terminus, followed by Flag tag and Avi tag Expression System HEK293 Molecular Weight 43 55kDa (Reducing) Purity 95% by SDS PAGE Conjugation Unconjugated
Product Specification
| Species | Human |
| Synonyms | CD3 epsilon&CD3 delta, CD3E & CD3D, CD3 delta & CD3 epsilon |
| Accession | P07766-1、P04234-1 |
| Amino Acid Sequence | Asp 23 - Asp 126 (CD3E) with hIgG1 Fc Tag at the C-Terminus, followed by polyhistidine tag and Avi tag |
| Expression System | HEK293 |
| Molecular Weight | 43-55kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Conjugation | Unconjugated |
| Tag | Avi Tag, His Tag, Flag Tag, Human IgG1 Fc |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1. Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function. Sci Rep. 2025 Feb 25;15(1):6769. |
Background
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
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Exchange/Return Notes
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