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Description
CD82 Recombinant Rabbit mAb (S-673-44)Product Specification Host Rabbit Synonyms CD82 antigen, C33 antigen, IA4, Inducible membrane protein R2, Metastasis suppressor Kangai 1, Suppressor of tumorigenicity 6 protein, Tetraspanin 27 (Tspan 27), KAI1, SAR2, ST6, TSPAN27 Immunogen Synthetic Peptide Location Cell membrane Accession P27701 Clone Number S 673 44 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg
Product Specification
| Host | Rabbit |
| Synonyms | CD82 antigen, C33 antigen, IA4, Inducible membrane protein R2, Metastasis suppressor Kangai-1, Suppressor of tumorigenicity 6 protein, Tetraspanin-27 (Tspan-27), KAI1, SAR2, ST6, TSPAN27 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P27701 |
| Clone Number | S-673-44 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC-P | 1:500 |
Background
CD82 is a membrane glycoprotein that is a member of the tetraspanin/transmembrane 4 superfamily. Expression of this protein has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients.
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