SKU: 34836224317

Mouse Anti-Human CD80 Antibody (S-3119)

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Description

Mouse Anti-Human CD80 Antibody (S-3119)Product Specification Host Mouse Antigen CD80 Synonyms T lymphocyte activation antigen CD80; Activation B7 1 antigen; BB1; CTLA 4 counter receptor B7. 1 (B7); CD28LG; CD28LG1; LAB7 Location Cell membrane Accession P33681 Clone Number S 3119 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Raji Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4

Product Specification


Host Mouse
Antigen CD80
Synonyms T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1 (B7); CD28LG; CD28LG1; LAB7
Location Cell membrane
Accession P33681
Clone Number S-3119
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Raji
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CD80, also known as B7-1, is a co-stimulatory molecule expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. It plays a crucial role in the immune response by interacting with CD28 on T cells to provide a necessary co-stimulatory signal for T cell activation. Additionally, CD80 can bind to CTLA-4, an inhibitory receptor on T cells, which serves as a negative regulatory mechanism to control the extent of the immune response. This dual functionality highlights the importance of CD80 in both initiating and modulating immune reactions, making it a key target in immunotherapy research for conditions such as cancer and autoimmune diseases.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 34836224317

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4.5 ★★★★★
Based on 21 reviews
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Product Reviews
J
Verified Purchase
J. Cobb
Phoenix, US
★★★★★ 5
Toughest ball of this type.
Color: Blue
My dogs are brutal with these toys. I really like them as the spikes act as a tooth brush, and the dogs love knawing on them. There are other spiked balls like this on amazon, but this one is of better quality. It lasts a lot longer. The squeaker does not last long, the dogs teeth push it into the ball, you can hear it rattling around in there.
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Reviewed in the United States on December 1, 2025
G
Verified Purchase
Georgia
Cuba, US
★★★★★ 4
Very good for aggressive chewers
Color: Red, Blue, Green, Yellow
Finally found ball that my aggressive chewer doesn't destroy. Has loud squeaker however he broke after 4 days. Probably better, noise gone. Very sturdy and he loves. Also big so doesn't roll under furniture.
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Reviewed in the United States on January 25, 2025
S
Verified Purchase
Samantha Anthony
San Leandro, US
★★★★★ 5
Durable
Color: Purple
I bought this for my 80lb 1yr American Bully male,who has made it his mission to test all the toys his dad and I have bought. Now I have 3 other American Bullies, siblings 3yr old 2 females/1male, who did the same at that age and I mastered toy shopping or so I thought. Lol. My new pup loves balls and this is the only one he firstly can't fit completely in his mouth and can't tear it apart. He has tired!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2026
T
Verified Purchase
TIFF
Lake Worth, US
★★★★★ 5
My Dogs Loved Them!
Color: Purple
My dogs loved these for playing fetch. They seem heavier duty than previous ones I have had. Beware of the incoming constant squeak sounds if your pup gets really into chewing it.
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Reviewed in the United States on May 8, 2026
K
Verified Purchase
Kingfam
Pawtucket, US
★★★★★ 5
Shockingly, good ball!
Color: Purple, Color: Purple
I have a Doberman. She is a ball and toy destroyer. She is the most obsessive retriever I’ve ever had. Her retrieving urge, and indefatigability, puts my golden retriever to shame. Because of this, we throw the ball all the time. She is primarily an indoor dog and we have to exhaust her energy and so throwing the ball is how this is done. I got these balls in an effort to try to find something that would last longer than a few days. I have now had these 2 balls for six weeks. They are both still alive! It literally blows my mind. When I bought them, we took bets on how long they would last. I gave it a week. I lost my bet. I got the extra large size. It’s perfect for the giant jaw span of a full grown Doberman. It squeaks, which is irritating to us, but what she loves. She can lay there and chew on it and still not destroy it. They’re very heavy ball and bounce, so you have to be careful throwing it in the house cause you could hurt breakables. Whoever said that these feel like they came from the dollar tree must have been talking about something else. They are thick and sturdy balls. UPDATE: it has now been THREE MONTHS and our Doberman STILL has not destroyed these 2 balls. We play with them many times each day. WORTH EVERY PENNY ADDITIONAL UPDATE: it’s now been nine months. Took this photo this morning. We still have the balls and have since ordered two more. She chews on it multiple times every day. There’s a little hole in it now and it doesn’t squeak anymore but it’s 98% intact and still essentially indestructible. These balls are worth gold.
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Reviewed in the United States on March 27, 2023

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