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Description
LYPD8 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms LYPD8, LY6, PLAUR domain containing 8 Accession Q6UX82 Amino Acid Sequence Leu20 Asn215, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | LYPD8, LY6, PLAUR domain containing 8 |
| Accession | Q6UX82 |
| Amino Acid Sequence | Leu20-Asn215, with C-terminal Human IgG1 Fc LSCVQCNSWEKSCVNSIASECPSHANTSCISSSASSSLETPVRLYQNMFCSAENCSEETHITAFTVHVSAEEHFHFVSQCCQGKECSNTSDALDPPLKNVSSNAECPACYESNGTSCHGKPWKCYEEEQCVFLVAELKNDIESKSLVLKGCSNVSNATCQFLSGENKTLGGVIFRKFECANVNSLTPTSAPTTSHNIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 60-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Okumura R. et al. (2020) Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia. Mucosal Immunol. 13: 75-85. |
Background
Lypd8 is a highly N-glycosylated glycosylphosphatidylinositol-anchored protein that is highly expressed on colonic IECs and constitutively shed into the intestinal lumen. Lypd8 inhibits the invasion of colonic epithelia by flagellated commensal bacteria such as Proteus mirabilis and E. coli belonging to Enterobacteriaceae family by suppressing their motility via flagella binding. However, it remains unclear whether Lypd8 has a protective function against pathogenic bacteria, including pathogenic E. coli, Salmonella, Shigella, and Citrobacter, many of which belong to the family Enterobacteriaceae.
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4.9 ★★★★★
Based on 11 reviews
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Product Reviews
★★★★★ 5
Great toy
Color: Red
She LOVES it
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 10, 2025
★★★★★ 5
Dogs love them!
Color: Blue
I had to by one for each one of my dogs after purchasing the first one for the new puppy. All three, pink, red, and blue are the same size fyi. Dogs love them and they seem very durable for my heavy chewers.
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Reviewed in the United States on April 27, 2025
★★★★★ 5
incredible
Color: #03 Champagne
Simply wonderful! The fragrance is delicate and sophisticated, leaving the skin gently scented all day long. The glitter has an elegant shine and is not exaggerated, perfect for parties or special events. The application is super practical, spreads easily and the fixation is great. I recommend it to those who want a touch of glamour and brightness with an incredible smell!
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Reviewed in the United States on February 26, 2026
★★★★★ 5
90’s me be jealous 🥹
Color: #04 Bronze
26 years later, here I am- the sparkling unicorn of an adult the late 90’s child version of myself DREAMED of while coating ✨EVERYTHING✨ in glitter and shimmer. Only now, I have an Amazon card and the impulse control of a toddler, so I sparkle now 🤩.
Am I 40 years old? Absolutely.
Did my kindergarteners at school ask why I sparkle now? Absolutely.
Did my mid-life crisis self lie to them, and say because I’m a magical unicorn? Absolutely.
Did they believe me? ABSOLUTELY.
10/10 recommend, but only if you too want to live your best magical unicorn life!
Technical notes- the smell is light and lovely. It dries without a “feel” so I forget I even have it on. The shimmer is noticeable, but not like I rolled in glitter. I’m enjoying the bronze glimmer color, but I’m sure will be back soon for more. I could easily spray more if I wanted to be more blatant with my attention seeking. I will absolutely be using this stuff from now until I’m in my grave with no shame!
Fantastic all around 🤌
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Reviewed in the United States on March 31, 2025
★★★★★ 1
super cute until it stops working
Color: #03 Champagne
worked really great for about 10 sprays before it clogged permanently! tried to clean out the spray mechanism but it still didn’t work.
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Reviewed in the United States on April 21, 2026