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Description
Alexa Fluor® 488 Rat Anti-Mouse TCR Vα2 Antibody (S-R698)Product Specification Host Rat Antigen TCR V2 Synonyms T cell receptor alpha chain constant; Trac Location Cell membrane Accession P01849 Clone Number S R698 Antibody Type Rat mAb Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rat |
| Antigen | TCR Vα2 |
| Synonyms | T-cell receptor alpha chain constant; Trac |
| Location | Cell membrane |
| Accession | P01849 |
| Clone Number | S-R698 |
| Antibody Type | Rat mAb |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
TCR Vα2 is a distinct TCR subfamily found in mice with a, b, and c haplotypes. It is a variable region of the T cell receptor (TCR) that plays a crucial role in recognizing antigens bound to major histocompatibility complex (MHC) molecules. The TCR Vα2 subfamily is often expressed in both CD4 and CD8 subsets of T cells, although its expression can be skewed to CD8 cells when combined with certain TCR β-chain transgenes. It is also involved in the positive selection of CD8+ T cells in the thymus.
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