SKU: 36429305443

Rat Anti-Mouse CD185 Antibody (S-R600)

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Description

Rat Anti-Mouse CD185 Antibody (S-R600)Product Specification Host Rat Antigen Mouse CD185 Synonyms C X C chemokine receptor type 5; CXC R5; CXCR 5; Burkitt lymphoma receptor 1 homolog; Cxcr5; Blr1; Gpcr6 Location Cell membrane Accession Q04683 Clone Number S R600 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7.

Product Specification


Host Rat
Antigen Mouse CD185
Synonyms C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1 homolog; Cxcr5; Blr1; Gpcr6
Location Cell membrane
Accession Q04683
Clone Number S-R600
Antibody Type Rat mAb
Isotype IgG2b,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:200 Ms

Background

CD185, also known as CXCR5 (C-X-C motif chemokine receptor 5), is a seven-transmembrane G protein-coupled receptor primarily expressed on mature B cells, follicular helper T cells (Tfh), and certain memory T cell subsets. It is essential for lymphocyte trafficking, particularly in directing T cells to B cell follicles within germinal centers in response to its ligand, CXCL13. CD185 plays a critical role in B cell maturation and the formation of high-affinity antibodies by facilitating interactions between Tfh cells and B cells. Additionally, it is involved in the regulation of neural stem cells and neuronal regeneration.

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SKU: 36429305443

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