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Description
TSLP His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms thymic stromal lymphopoietin; Accession A0A7N9CAT7 Amino Acid Sequence Tyr29 Gln159, with His tag at the C Terminus. Expression System HEK293 Molecular Weight The protein has a predicted MW of 16. 3 kDa. Due to furin cleavage site, the protein migrates to 12 kDa&23 30 kDa based on Bis Tris PAGE result. Purity > 95% as determined by Bis Tris PAGE & > 90% as determined by HPLC Endotoxin <1EU g
Product Specification
| Species | Cynomolgus |
| Synonyms | thymic stromal lymphopoietin; |
| Accession | A0A7N9CAT7 |
| Amino Acid Sequence | Tyr29-Gln159, with His tag at the C-Terminus. |
| Expression System | HEK293 |
| Molecular Weight | The protein has a predicted MW of 16.3 kDa. Due to furin cleavage site, the protein migrates to 12 kDa&23-30 kDa based on Bis-Tris PAGE result. |
| Purity | > 95% as determined by Bis-Tris PAGE & > 90% as determined by HPLC |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
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