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Description
SBDS Recombinant Rabbit mAb (S-R344)Product Specification Host Rabbit Synonyms Shwachman Bodian Diamond syndrome protein Location Cytoplasm, Nucleolus Accession Q9Y3A5 Clone Number S R344 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC, ICFCM, IHC Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Synonyms | Shwachman-Bodian-Diamond syndrome protein |
| Location | Cytoplasm, Nucleolus |
| Accession | Q9Y3A5 |
| Clone Number | S-R344 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC, ICFCM, IHC |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:2000 | null |
| IHC-P | 1:500 | null |
| ICC | 1:500 | null |
| ICFCM | 1:500 | null |
Background
SBDS (SBDS Ribosome Maturation Factor) is ubiquitously expressed in heart, fat and other tissues. SBDS is required for mature ribosome assembly and ribosome biogenesis and is required for 60S rRNA processing and nuclear export. SBDS plays a role in cellular response to DNA damage, cellular stress resistance, and cell proliferation. SBDS is related to rRNA binding and some diseases, including Shwachman-Diamond Syndrome 1 and Aplastic Anemia.
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