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Description
Biotin Mouse anti-Human CD36 Antibody (S-R617)Product Specification Host Mouse Antigen CD36 Synonyms Platelet glycoprotein 4; Fatty acid translocase (FAT); Glycoprotein IIIb (GPIIIB); Leukocyte differentiation antigen CD36; PAS IV; PAS 4; GP3B; GP4 Location Cell membrane Accession P16671 Clone Number S R617 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral blood cells Purification Protein G Concentration 0. 02mg ml Conjugation Biotin Physical
Product Specification
| Host | Mouse |
| Antigen | CD36 |
| Synonyms | Platelet glycoprotein 4; Fatty acid translocase (FAT); Glycoprotein IIIb (GPIIIB); Leukocyte differentiation antigen CD36; PAS IV; PAS-4; GP3B; GP4 |
| Location | Cell membrane |
| Accession | P16671 |
| Clone Number | S-R617 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood cells |
| Purification | Protein G |
| Concentration | 0.02mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD36 is a multifunctional transmembrane glycoprotein belonging to the class B scavenger receptor family, widely expressed in various cell types including macrophages, endothelial cells, adipocytes, and muscle cells. It plays a crucial role in fatty acid uptake and transport, acting as a receptor for a diverse range of ligands such as oxidized low-density lipoprotein (oxLDL), apoptotic cells, thrombospondin, and pathogens like malaria-infected erythrocytes. Structurally, CD36 is a heavily glycosylated protein with two transmembrane domains, a large extracellular loop, and short intracellular tails. Its functions span from facilitating lipid metabolism and mediating immune responses to contributing to pathological conditions like atherosclerosis and diabetes. Additionally, CD36 is involved in cellular signaling pathways related to inflammation and angiogenesis.
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