Pay in installments of $30.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 25 - Aug 30
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Biotin Rat Anti-Mouse CD184 Antibody (S-R670)Product Specification Host Rat Antigen CD184 Synonyms C X C chemokine receptor type 4; CXC R4; CXCR 4; Fusin; Leukocyte derived seven transmembrane domain receptor (LESTR); Pre B cell derived chemokine receptor (PB CKR); Stromal cell derived factor 1 receptor (SDF 1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4 Location Cell membrane Accession P70658 Clone Number S R670 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL
Product Specification
| Host | Rat |
| Antigen | CD184 |
| Synonyms | C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4 |
| Location | Cell membrane |
| Accession | P70658 |
| Clone Number | S-R670 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.5 mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1μg per million cells in 100μl volume | Ms |
Background
CD184, also known as CXCR4, is a seven-transmembrane G-protein-coupled chemokine receptor that—after binding its unique ligand CXCL12 (SDF-1)—triggers multiple signaling cascades (PI3K/AKT, JAK/STAT, ERK1/2, Hedgehog) governing immune cell trafficking, plasma-cell homing to bone-marrow niches, embryonic development, hematopoiesis, angiogenesis, and cancer stem-cell maintenance, while its overexpression or mutations underlie WHIM syndrome, HIV entry, tumor progression and metastasis, making it a key therapeutic target in oncology and immunology.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy