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Description
S-RMab® CD79B Recombinant Rabbit mAb,PBS Only (SDT-R513)Product Specification Host Rabbit Antigen CD79B Synonyms B cell antigen receptor complex associated protein beta chain, B cell specific glycoprotein B29, Ig beta, Immunoglobulin associated B29 protein, B29, IGB Location Cell membrane Accession P40259 Clone Number SDT R513 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IP, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | CD79B |
| Synonyms | B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, B29, IGB |
| Location | Cell membrane |
| Accession | P40259 |
| Clone Number | SDT-R513 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IP, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:4000 | |
| IP | 1:200 | |
| IHC-P | 1:250 | |
| ICC | 1:2000 | |
| ICFCM | 1:2000 |
Background
CD79B is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. And it also enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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