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Description
PE Mouse Anti-Human CD54 Antibody (S-3807)Product Specification Host Mouse Antigen CD54 Synonyms Intercellular adhesion molecule 1; ICAM 1; Major group rhinovirus receptor; ICAM1 Location Membrane Accession P05362 Clone Number S 3807 Antibody Type Mouse mAb Isotype IgG2a Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 0. 1 mg ml Conjugation PE Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months
Product Specification
| Host | Mouse |
| Antigen | CD54 |
| Synonyms | Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; ICAM1 |
| Location | Membrane |
| Accession | P05362 |
| Clone Number | S-3807 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein A |
| Concentration | 0.1 mg/ml |
| Conjugation | PE |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1μl per million cells in 100μl volume | Hu |
Background
CD54 is an 85–110 kDa transmembrane glycoprotein of the immunoglobulin superfamily that is expressed on endothelial, epithelial and immune cells; upon binding its ligands LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) it serves as the critical adhesion checkpoint that promotes firm leukocyte arrest on the vessel wall, enables subsequent diapedesis into inflamed tissue, and amplifies antigen-specific T-cell activation, thereby positioning it at the mechanistic center of inflammatory, autoimmune and anti-tumor immune responses.
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Exchange/Return Notes
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