SKU: 43505357827

UBE2F Recombinant Rabbit mAb (S-2672-26)

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Description

UBE2F Recombinant Rabbit mAb (S-2672-26)Product Specification Host Rabbit Antigen UBE2F Synonyms NEDD8 conjugating enzyme UBE2F; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8 conjugating enzyme 2; RING type E3 NEDD8 transferase UBE2F; Ubiquitin conjugating enzyme E2 F; NCE2 Immunogen Synthetic Peptide Location Nucleus Accession Q969M7 Clone Number S 2672 26 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Positive Sample

Product Specification


Host Rabbit
Antigen UBE2F
Synonyms NEDD8-conjugating enzyme UBE2F; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; RING-type E3 NEDD8 transferase UBE2F; Ubiquitin-conjugating enzyme E2 F; NCE2
Immunogen Synthetic Peptide
Location Nucleus
Accession Q969M7
Clone Number S-2672-26
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P, ICC, ICFCM
Reactivity Hu, Ms, Rt
Positive Sample Jurkat, A375, HeLa, HL-60, NTERA2, RAW264.7, NIH/3T3, mouse testis, rat ovary, rat testis
Predicted Reactivity Bv
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt
IHC-P 1:1000 Hu, Ms, Rt
ICC 1:500 Hu, Ms
ICFCM 1:50 Hu, Ms

Background

UBE2F (ubiquitin-conjugating enzyme E2 F) is a NEDD8-specific E2 conjugating enzyme that, following activation by the NAE1–UBA3 heterodimer, transfers NEDD8 onto CRL5–RBX2/SAG complexes to catalyze CUL5 neddylation, thereby activating CRL5 E3 ligase activity and promoting K11-linked polyubiquitylation and proteasomal degradation of the pro-apoptotic protein NOXA, a pathway that is frequently up-regulated in non-small-cell lung cancer to suppress apoptosis and drive tumor survival, and whose oncogenic action can be pharmacologically targeted to enhance chemotherapy sensitivity.

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Exchange/Return Notes
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SKU: 43505357827

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4.8 ★★★★★
Based on 15 reviews
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J
Verified Purchase
James moore
Draper, US
★★★★★ 5
Excellent value
Color: Green, Style: AE1000W-3AV
Nice watch typical Casio quality for a excellent price
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 4, 2026
T
Verified Purchase
Thomas S
Whiting, US
★★★★★ 3
The little watch that tried...and almost succeeded.
Color: Black/Black, Style: AE1000W-1BVCF
The main problem with this watch for me is it tries to do too much and relies heavily on the user. With Day light Savings time not being universal in when it starts, when it ends, and which countries decide to use it, it is a lot of work for some functions Day Light Savings time really hurts this watch and what it tries to do. This Casio watch is priced right and pleasant to look at. It has four main functions\modes. 1 Timekeeping 2 World Time 3 Stop watch 4 Alarm I'll focus on the first 2 as this is where it shines and falls short for me. In TIME KEEPING mode --Works Great You can set 4 different times and tab through them with the bottom right button. This is very useful and quite easy to set up. Upon setting up your local time the next three will be based off that and you only need to set Day Light Savings time on or off accordingly. This is easy to maintain and the world map reflects the time zone you are currently in. In WORLD TIME mode you can quickly tab through over 40 cities around the globe. This is where the watch falls short. You need to set each city depending on their Day Light Savings time. Some cities do not use DST, some start in the middle of March, Some start at end of March, ect.. If you do not mind doing this for each city in WORLD TIME which will require you to look up each of their DST information then this is a nice function. I'm not at all interested in doing this. This is a function an atomic watch would excel at but a manual setting watch it's not worth the effort The rest of the features are more than gimmicks. The world map is functional, especially if you set the DST for each of the cities in WORLD TIME. The analog dial always shows your current time no matter what mode you are in or which of the 4 cities you are on in TIME KEEPING mode.The light is unbalanced but sufficient to light the entire dial. You can change it to 3 seconds from it's factory 1.5 seconds which makes it much more useful. If you want this watch to keep track the current time in four cities it is very easy to set up and works quite well.
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Reviewed in the United States on March 10, 2014
R
Verified Purchase
Rebecca
Chelsea, US
★★★★★ 5
Well made, high quality wallet
Size: One Size, Color: Brown
I bought this for my husband for Father's Day. It's a beautiful, well made, quality wallet. The stitching is heavy duty and the leather is very nice. It isn't bulky. A few months of having it and it seems to have broken in well.
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Reviewed in the United States on November 13, 2025
S
Verified Purchase
Shannon Congdon
Boise, US
★★★★★ 5
Good wallet all around!
Size: One Size, Color: Brown
I needed a new wallet, it was here, its durable and going to last a while, it has everything I need it to. Theres two spots for where traditionally cash would go, which is nice, and a lot of spots for cards or IDs! Pretty safe, all I've lost is coins when it's upside down when I have too many so thats a good sign! It did have a 'new leather' smell when I got it, but it has gone away after a while, and it looks great! The leather feels and looks high quality! I didn't even know there were magnets, so I cant review them, woops.
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Reviewed in the United States on July 14, 2025
M
Verified Purchase
Mike Norman
Whiting, US
★★★★★ 5
Excellent Men's Wallet
Size: One Size, Color: Brown
Nicely priced men's tri-fold wallet. Everything I want to carry, which is actually too much stuff, fits into this wallet.
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Reviewed in the United States on December 27, 2025

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