SKU: 45386909558

CD3 epsilon&CD3 delta Heterodimer Fc, His Tag&Fc, Flag Tag Protein, Human

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Description

CD3 epsilon&CD3 delta Heterodimer Fc, His Tag&Fc, Flag Tag Protein, HumanProduct Specification Species Human Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D Accession P07766 1(CD3E)P04234 1(CD3D) Amino Acid Sequence Asp 23 Asp 126 (CD3E) with hIgG1 Fc Tag at the C Terminus, followed by His Tag Phe 22 Ala 105 (CD3D) with hIgG1 Fc Tag at the C Terminus, followed by Flag Tag Expression System HEK293 Molecular Weight 40 55kDa (Reducing) Purity 95% by SDS PAGE & HPLC Conjugation Unconjugated Tag His Tag, Flag Tag, Human IgG1 Fc

Product Specification


Species Human
Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D
Accession P07766-1(CD3E)、P04234-1(CD3D)
Amino Acid Sequence

Asp 23 - Asp 126 (CD3E) with hIgG1 Fc Tag at the C-Terminus, followed by His Tag
Phe 22 - Ala 105 (CD3D) with hIgG1 Fc Tag at the C-Terminus, followed by Flag Tag

Expression System HEK293
Molecular Weight

40-55kDa (Reducing)

Purity >95% by SDS-PAGE & HPLC
Conjugation Unconjugated
Tag His Tag, Flag Tag, Human IgG1 Fc
Physical Appearance Lyophilized powder
Storage Buffer

PBS, PH7.4, 5% trehalose

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Reference

1. Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function. Sci Rep. 2025 Feb 25;15(1):6769.
2. A rationally designed fully human EGFRvIII:CD3-targeted bispecific antibody redirects human T cells to treat patient-derived intracerebral malignant glioma.[J]. Clinical Cancer Research, 2018:clincanres.0126.2017.

Background

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 45386909558

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4.7 ★★★★★
Based on 18 reviews
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P
Verified Purchase
Pamela G
Omaha, US
★★★★★ 1
Easily Ripped apart within minutes
Color: Blue Puppy, Size: Medium Size 2, Color: Blue Puppy, Size: Medium Size 2
I have a new foster who’s only 35 pounds not an aggressive chewer and loves to play with my dogs rooster soccer ball toy but the ball itself is a little big for her to get her teeny little mouth around when she’s trying to carry and run with it this happened to pop up on my feed a size smaller (medium, instead of large ) and available for next day delivery, so I bought it specifically for the little dog to play with. I gave it to her to play outside while my hound is busy playing with one of her toys I went about watering the garden, when I turned around a few minutes later, I saw the ball appeared to be completely flattened. As I walked over, I saw pieces of black rubber on the ground, and then the rest of the ball had a gaping hole in it. The rooster version of the ball that I bought from another seller has been going strong for months with multiple dogs playing with it and chewing on it and ripping the side ribbons apart so either I got a defective toy or the quality of manufacturer from this seller is much lower since the durability of the ball seems to be less than an hour.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 24, 2025
C
Verified Purchase
Cmb galdamez
Waukegan, US
★★★★★ 5
Great ball
Color: Blue Puppy, Size: Medium Size 2
My babies love it
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 14, 2026
T
Verified Purchase
Tiff
Chelsea, US
★★★★★ 2
Not very durable
Color: Blue Puppy, Size: Medium Size 2
This ball is cute and my dog loves tags. However he popped this ball with one bite to carry it…. Within 10 minutes of getting it. It should have a tougher exterior
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 25, 2025
B
Verified Purchase
Beach Lover (Sue)
Houston, US
★★★★★ 5
Pup loves this!
Size: 6 Inch, Color: Red
This soccer ball is so cute. My dog loves to play with these. The straps are durable, easy to pump up (they come with a pump), good value for the money since they tend to last awhile, at least for us. The straps are durable but could be an issue if your dog is an aggressive chewer. They stay pumped up for quite awhile and just need to be topped off once in awhile to keep the bounce there. We keep them outside even in the winter and they do just fine. HIghly recommend as a good play toy.
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Reviewed in the United States on December 16, 2025
K
Verified Purchase
KDDYOUMANS
Los Angeles, US
★★★★★ 5
Great Ball
Size: 6 Inch, Color: Red
Our Little Goldendoodle Loves this ball & I like that it has so many straps to grab so I'm not getting the slimy part. It does not come already inflated so make sure you or a neighbor have an air compressor to blow it up because even though it came with a little pump I can't imagine how many weeks I'd have been pumping that without noticing any difference.
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Reviewed in the United States on May 2, 2026

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