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Description
CD66b Recombinant Rabbit mAb (S-766-55)Product Specification Host Rabbit Synonyms Carcinoembryonic antigen related cell adhesion molecule 8, CD67 antigen, Carcinoembryonic antigen CGM6, Non specific cross reacting antigen NCA 95, CEACAM8, CGM6 Immunogen Recombinant Protein Location Cell membrane Accession P31997 Clone Number S 766 55 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Synonyms | Carcinoembryonic antigen-related cell adhesion molecule 8, CD67 antigen, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, CEACAM8, CGM6 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P31997 |
| Clone Number | S-766-55 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | null |
Background
CD66b, also known as CEACAM8, is a cell surface glycoprotein that is primarily expressed on granulocytes and is involved in various immune functions. It has been found to be expanded in patients with Waldenstrom macroglobulinemia (WM) and exhibits a unique inflammatory transcriptome. And the main function of CD66b is cell adhesion, cell migration, and pathogen binding. CD66b molecules were localized in lipid rafts, and disruption of lipid rafts or removal of the GPI anchor inhibited the adhesion and activation of eosinophils.
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