SKU: 45819483289

Alexa Fluor® 488 Rat Anti-Mouse CD25 (IL-2Rα) Antibody (S-3558)

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Description

Alexa Fluor® 488 Rat Anti-Mouse CD25 (IL-2Rα) Antibody (S-3558)Product Specification Host Rat Antigen CD25 Synonyms Interleukin 2 receptor subunit alpha; IL 2 receptor subunit alpha; IL 2 RA; IL 2R subunit alpha; IL2 RA; p55; Il2r; Il2ra Location Membrane Accession P01590 Clone Number S 3558 Antibody Type Rat mAb Isotype IgG1, Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer

Product Specification


Host Rat
Antigen CD25
Synonyms Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; p55; Il2r; Il2ra
Location Membrane
Accession P01590
Clone Number S-3558
Antibody Type Rat mAb
Isotype IgG1,λ
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Ms

Background

CD25, also known as the interleukin-2 receptor alpha chain (IL2RA), is a type I transmembrane glycoprotein that plays a crucial role in the immune system. It is primarily expressed on the surface of activated T cells and regulatory T cells (Tregs). CD25 is a key component of the high-affinity IL-2 receptor complex, which also includes the IL-2 receptor beta and gamma chains. By itself, CD25 can bind IL-2 with low affinity, but when combined with the beta and gamma chains, it forms a high-affinity receptor that initiates intracellular signaling pathways such as MAPK and JAK/STAT. This receptor complex is essential for the proliferation and activation of T cells, as well as the regulation of immune tolerance by controlling the activity of Tregs. Mutations in the IL2RA gene can lead to deficiencies in IL-2 receptor function, highlighting its importance in maintaining immune homeostasis.

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SKU: 45819483289

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Jennay
Omaha, US
★★★★★ 5
Mens shirt
Size: 17"-17.5" Neck 36"-37" Sleeve, Color: Lavender Blue Check
It's a very well made shirt. I got it for my husband, he has to wear this kinda stuff for work. He actually loves this brand of shirt. Very comfortable. I actually got it on Amazon days or whatever it's called. So the price was cheaper than normal:)
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Reviewed in the United States on August 13, 2025
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Joe Anderson
Pawtucket, US
★★★★★ 5
My original dress shirt in white.
Size: 15"-15.5" Neck 34"-35" Sleeve, Color: Grey Sage Check
Tried and true dress shirt but I love how the collar stays are actually sewn into the collar.
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Reviewed in the United States on October 29, 2025
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London the Goldie
Houston, US
★★★★★ 4
Nice shirt. Sleeves ran a little short.
Nice shirt,but make sure your sleeve length is correct.
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Reviewed in the United States on May 1, 2025
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Amazon Customer
Belleville, US
★★★★★ 5
Men's shirt
Nice quality shirt.
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Reviewed in the United States on October 24, 2025
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marcia bouray
Lowell, US
★★★★★ 5
You wanted an opinion
Size: 17"-17.5" Neck 32"-33" Sleeve, Color: Blue Rain Print
It worked out well
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Reviewed in the United States on October 10, 2025

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