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Description
Monkey IgM OneStep ELISA KitProduct Specification Antigen IgM Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Mk Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 2. 8% Inter assay: 3. 8% Sample type Cell culture supernatant, Serum, Plasma Assay type Sandwich (quantitative) Sensitivity 0. 246 ng ml Range 0. 469 ng mL 30 ng mL Recovery Cell culture supernatant: 91%
Product Specification
| Antigen | IgM |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Mk |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 2.8%； Inter-assay: 3.8% |
| Sample type | Cell culture supernatant, Serum, Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 0.246 ng/ml |
| Range | 0.469 ng/mL – 30 ng/mL |
| Recovery | Cell culture supernatant: 91% Serum: 90% Plasma: 90% |
| Assay time | 60 minutes |
| Species reactivity | Monkey |
Background
Monkey IgM, the largest antibody isotype with a pentameric structure (approximately 900 kDa) and 10 antigen-binding sites, serves as the essential first line of defense in the primary immune response, mediating initial pathogen neutralization and complement activation while being largely confined to the serum compartment due to its size. In monkeys (e.g., Macaca mulatta), IgM-positive B-cells develop progressively from low levels in infants, reaching near-adult levels around 5 months, with highly variable expression (26.3–94.9%) observed in adults—a critical factor for baseline screening in research models like transplantation studies. Careful sample handling (centrifugation, storage at -70°C) and awareness of assay cross-reactivity are important technical considerations. Commercially available kits and reagents enable precise quantification and analysis across clinical diagnostics and biomedical research, underscoring IgM's critical role in primate immunity.
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