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Description
MIP-4/CCL18 Protein, HumanProduct Specification Species Human Synonyms AMAC 1,PARC,DC CK1 Accession P55774 Amino Acid Sequence Ala21 Ala89 Expression System E. coli Molecular Weight Approximately 7. 9 kDa, a single non glycosylated polypeptide chain containing 69 amino acids. Purity 96% by SDS PAGE or HPLC. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH 7. 0. Reconstitution Before use this product, please read the direction
Product Specification
| Species | Human |
| Synonyms | AMAC-1,PARC,DC-CK1 |
| Accession | P55774 |
| Amino Acid Sequence | Ala21-Ala89 |
| Expression System | E.coli |
| Molecular Weight | Approximately 7.9 kDa, a single non-glycosylated polypeptide chain containing 69 amino acids. |
| Purity | ＞96% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, pH 7.0. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61 % sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues like lymph nodes express CCL18 at low level. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. Involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cell mediated immunity responses. Recombinant Human MIP-4/CCL18 is a 7.9kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines
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