SKU: 47020047701

Biotin Armenian hamster Anti-Mouse CD11c Antibody (S-R518)

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Description

Biotin Armenian hamster Anti-Mouse CD11c Antibody (S-R518)Product Specification Host Armenian hamster Antigen Mouse CD11c Synonyms Integrin alpha X; CD11 antigen like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax Location Membrane Accession Q9QXH4 Clone Number S R518 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation

Product Specification


Host Armenian hamster
Antigen Mouse CD11c
Synonyms Integrin alpha-X; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax
Location Membrane
Accession Q9QXH4
Clone Number S-R518
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD11c, also known as the integrin alpha X chain, is a type I transmembrane glycoprotein and a component of the complement receptor 4 (CR4). CD11c is primarily expressed on myeloid dendritic cells (DCs) and acts as a positive regulator in the adhesion, migration, antigen recognition, and presentation processes, leading to the activation of CD4+ and CD8+ T cells. It is not only expressed on dendritic cells but also on other immune cells such as alveolar macrophages and cells in adipose tissue. In humans, monocytes and dendritic cells can both express CD11c. Additionally, CD11c expression has been detected in a subset of gut macrophages, neutrophils during inflammation, a small fraction of B cells (mainly in autoimmune diseases), natural killer cells, and T cell subsets. In diseased brains, activated microglia can also express CD11c. CD11c forms a heterodimer with CD18, belonging to the β2 integrin family, and together with CR3 (comprising CD11b and CD18), it is involved in cell adhesion, migration, and phagocytosis. CR3 and CR4 have overlapping ligand-binding specificities and bind to various ligands such as fibrinogen or heparin. In oncology, CD11c is an important marker for diagnosing hairy cell leukemia, acute myeloid leukemia, and some chronic lymphocytic leukemias. Furthermore, the expression of CD11c is associated with liver inflammation and microglial activation.

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SKU: 47020047701

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4.1 ★★★★★
Based on 10 reviews
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Elizabeth from Houston
Battle Creek, US
★★★★★ 5
Helps with redness and softens skin
I have sensitive, mild rosacea skin. Had a facial recently and the aesthetician suggested I get a serum to help with moisturizer as I am almost 40. I’ve tried a lot of serums and either they are sticky and not really hydrating or break my skin out in a rash. This serum is amazing. Helps calm the redness in my cheeks and my skin is moisturized and soft all day. It feels a little sticky at first but it goes away. I apply in this order OSEA sea mineral mist toner to prep the skin, this serum and top off with Chanel La Solution 10 for sensitive skin.
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Reviewed in the United States on December 27, 2025
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carolyn
San Leandro, US
★★★★★ 5
Sensitive skin
Such a good product. I use after micro needling when skin is sensitive. Also a great product to use as a barrier serum when starting tretinoin cream.
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Reviewed in the United States on April 24, 2026
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Lindsay
Charlottesville, US
★★★★★ 5
Saved my skin during an eczema flare up
This saved my skin! I had an eczema flare on my face, and my usual products weren’t working. A friend recommended the Avene brand and within 3 days of using this rescue barrier serum, my flare was almost completely gone! This saved my face!
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Reviewed in the United States on April 11, 2026
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Verified Purchase
B Helton
Birmingham, US
★★★★★ 1
PLEASE REVIEW — FORMULA CHANGED!!!
I wish I would’ve posted a review PRIOR to the formula changing but just know that I LOVED this serum. I’ve struggled with hormonal acne (PCOS) and eczema for as long as I can remember. Finally, last summer my dermatologist put me on (3) different RX including Spironolactone and Accutane. I was so tired so I stopped everything except for CeraVe cleanser, retinol (Tretinoin) and CeraVe healing ointment. My made up skin routine was working until I used too much Tretinoin and burned my face. I had read great reviews about this product so I thought, I might as well try it — and IT WORKED! I’ve been using this product for almost a year and I loved it. However, 3 weeks ago when I ordered it, I noticed the bottle had a green tint. I could tell after one use that the feel of the serum was different, more watery, not as thick as it used to be. The smell was also different. Still, I kept using it for nearly 2 weeks and I experienced 2 breakouts! Sure enough, I stopped the product and within a few days, my skin was back to normal. I am very upset because as someone who has extremely sensitive skin, this worked but unfortunately, the new formula isn’t for me.
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Reviewed in the United States on May 14, 2026
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sandraday
San Leandro, US
★★★★★ 5
Not greasy and no fragrance
Style: Updated Formula
Excellent moisturizer for my sensitive skin.
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Reviewed in the United States on May 26, 2026

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