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Description
CEACAM6 Recombinant Rabbit mAb (S-720-54)Product Specification Host Rabbit Antigen CEACAM6 Synonyms Carcinoembryonic antigen related cell adhesion molecule 6, Non specific crossreacting antigen, Normal cross reacting antigen, CD66c, NCA Immunogen Synthetic Peptide Location Cell membrane Accession P40199 Clone Number S 720 54 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | CEACAM6 |
| Synonyms | Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen, CD66c, NCA |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P40199 |
| Clone Number | S-720-54 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:500 |
Background
Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen (CEA) family. Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family are transmembrane glycoproteins that belong to the immunoglobulin superfamily. They are involved in several biological processes, such as cell growth, differentiation, cell recognition, immune response, and adhesion [7-10]. Different members of the CEACAM family may have different functions. There are four members of CEACAMs (namely, CEACAM1, CEACAM5, CEACAM6 and CEACAM7) have been found in epithelia. Theses CEACAMs members can mediate several cell signaling pathways and lead to various functions, such as tumor suppression/promotion, angiogenesis, lymphocyte activation, cell cycle and adhesion.
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