Pay in installments of $27.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 26 - Aug 31
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Rat Anti-Mouse CD198 Antibody (S-R626)Product Specification Host Rat Antigen CD198 Synonyms C C chemokine receptor type 8; C C CKR 8; CC CKR 8; CCR 8; CDw198; Cmkbr8; Ter1; Ccr8 Location Cell membrane Accession P56484 Clone Number S R626 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse thymocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA,
Product Specification
| Host | Rat |
| Antigen | CD198 |
| Synonyms | C-C chemokine receptor type 8; C-C CKR-8; CC-CKR-8; CCR-8; CDw198; Cmkbr8; Ter1; Ccr8 |
| Location | Cell membrane |
| Accession | P56484 |
| Clone Number | S-R626 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse thymocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD198, also known as C-C chemokine receptor type 8 (CCR8), is a 41 kD G-protein coupled receptor with seven transmembrane regions. It belongs to the C-C chemokine receptor family and is expressed in various cell types, including a subset of thymocytes, Tregs, NKT cells, Th2-polarized cells, macrophages, monocytes, and monocyte-derived dendritic cells. CCR8 plays a crucial role in mediating chemotaxis and is involved in the apoptosis of thymocytes. It is also associated with allergic inflammation and has potential as a therapeutic target for conditions like HIV-1 infection. The receptor binds to ligands such as CCL1 and CCL16 and has high affinity for viral chemokines like vMIP-I, vMIP-II, and vMCC-I.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy