SKU: 49250460497

GARP&Latent TGF-β1 Heterotrimer His Tag Protein, Mouse

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Description

GARP&Latent TGF-β1 Heterotrimer His Tag Protein, MouseProduct Specification Species Mouse Synonyms RRC32 & TGF beta 1; LRRC32&TGFB1 Accession G3XA59P04202 Amino Acid Sequence GARP: Ile18 Asn628, with C terminal His Latent TGF 1: Leu30 Ser390 Expression System HEK293 Molecular Weight 80 93kDa GARP(Reducing), 35 50kDa LAP(Reducing), 10 14kDa mature TGF 1 (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7.

Product Specification


Species Mouse
Synonyms RRC32 & TGF-beta 1; LRRC32&TGFB1
Accession G3XA59、P04202
Amino Acid Sequence

GARP: Ile18-Asn628, with C-terminal His Latent TGF-β1: Leu30-Ser390

Expression System HEK293
Molecular Weight

80-93kDa GARP(Reducing), 35-50kDa LAP(Reducing), 10-14kDa mature TGF-β1 (Reducing)

Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH7.4.

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Reference

1. Alessandra Metelli, Mohammad Salem, Caroline H Wallace, Bill X Wu, Anqi Li. Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer. J Hematol Oncol. 2018 Feb 20;11(1):24.

Background

GARP (glycoprotein-A repetitions predominant) is a type I transmembrane cell surface docking receptor for latent transforming growth factor-β (TGF-β) that is abundantly expressed on regulatory T lymphocytes and platelets. By binding to LTGF-β, GARP acts as a docking receptor that concentrates LTGF-β on the cell surface and enhances its final activation. The function of GARP has been extensively studied on regulatory T lymphocytes (Tregs), where it complexes with αVβ8 integrins to release active TGF-β from the surface of the cells. Via this function, GARP was shown to be involved in enhancing the suppressive phenotype of Tregs and in maintaining Treg-mediated peripheral tolerance.

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SKU: 49250460497

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Anthony Carabello
Birmingham, US
★★★★★ 4
Nice shirt!
Fit Type: Regular Fit, Color: White, Size: X-Large
I added one of these shirts to another order just to see if they were any good. I was pleasantly surprised by the quality. It fits perfectly and looks pretty nice for a low cost casual dress shirt. Materials seem decent quality. Comfortable, soft fabric. Didn’t shrink too much in the washer and dryer. We’ll see how it holds up long term but so far so good
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Reviewed in the United States on November 12, 2025
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madison
Lexington, US
★★★★★ 5
nice quality
Fit Type: Regular Fit, Color: White, Size: Small
nice quality shirt. bought this just so i had at least one nice white button down and it's great. fits well and is a nice white color.
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Reviewed in the United States on April 11, 2026
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Silvia & Marcus
Grantham, US
★★★★★ 5
My new favorite shirts!
Fit Type: Regular Fit, Color: Grey, Size: Large
These are my new favorite shirts! I just ordered a 3rd. i wish there were more colors. Yes, the cotton is heavy-weight and I like that. They are just a bit warmer than regular dress shirts. The fit is excellent. I'm 5'9", 200lbs and L fits perfectly. Enough room without being blousy. The sleeves are long enough (finally!). (Most other 16.5/32-33 shirts always have sleeves that are too short). The fit/finish and detail is surprisingly good. They don't really shrink after washing and come out very soft. Not wrinkle-free, but that's ok since it means that the 100% cotton hasn't been dosed with chemicals. I expect they will wear very well over time.
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Reviewed in the United States on May 5, 2025
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Blusher
Port Orchard, US
★★★★★ 3
Right fit
I love this shirt it was nice and bright when I got it after a few wash it started to fade out a bit was a perfect fit for a medium built person 5’7 I still would recommend this product they are really nice and thick
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Reviewed in the United States on September 14, 2025
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Linda Mokkosian
New York, US
★★★★★ 5
Excellent value and has saved me from the sun!
Fit Type: Regular Fit, Color: White, Size: Large
I ordered this large mans shirt because it was 100% cotton and long sleeve. I am a woman and use it to protect myself from the sun walking my dog, very stiff at first, but comes out with several washes. I love the shirt!
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Reviewed in the United States on June 9, 2026

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