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Description
Progesterone Receptor Recombinant Rabbit mAb (Alex Fluor®488 Conjugate) (S-R123)Product Specification Host Rabbit Antigen Progesterone Receptor Synonyms PR, NR3C3 Location Cytoplasm, Nucleus Accession P06401 Clone Number S R123 Antibody Type Recombinant mAb Application ICC, ICFCM Reactivity Hu Purification Protein A Concentration 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 01% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied.
Product Specification
| Host | Rabbit |
| Antigen | Progesterone Receptor |
| Synonyms | PR, NR3C3 |
| Location | Cytoplasm, Nucleus |
| Accession | P06401 |
| Clone Number | S-R123 |
| Antibody Type | Recombinant mAb |
| Application | ICC, ICFCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICC | 1:500 | null |
| ICFCM | 1:200 | null |
Background
Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls developmental processes and proliferation and differentiation during the reproductive cycle and pregnancy. PR also plays a role in progression of endocrine-dependent breast cancer. As a member of the nuclear receptor family of ligand-dependent transcription factors, the main action of PR is to regulate networks of target gene expression in response to binding its cognate steroid hormone, progesterone [PMID: 27380738].
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