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Description
VEGF-C Recombinant Rabbit mAb (SDT-084-66)Product Specification Host Rabbit Antigen VEGF C Synonyms Vascular endothelial growth factor C, Flt4 L, VRP Immunogen Recombinant Protein Accession P49767 Clone Number SDT 084 66 Antibody Type Rabbit mAb Application Sandwich ELISA Reactivity Hu Cross Reactivity Does not recognize VEGF 121, VEGF 165 Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Physical Appearance Liquid Storage Buffer PBS, pH 7. 4, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | VEGF-C |
| Synonyms | Vascular endothelial growth factor C, Flt4-L, VRP |
| Immunogen | Recombinant Protein |
| Accession | P49767 |
| Clone Number | SDT-084-66 |
| Antibody Type | Rabbit mAb |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | Does not recognize VEGF-121, VEGF-165 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, pH 7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Background
Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. The main function of VEGF-C is to promote the growth of lymphatic vessels (lymphangiogenesis). It acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration. In human tumour tissue samples VEGF-C was detected in some carcinomas in the low protein range. The ELISA will be a useful tool for investigations concerning the physiological function of VEGF-C in lymphangiogenesis under normal and pathophysiological conditions.
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