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Description
RNA polymerase II CTD repeat YSPTSPS (phospho S7) Recombinant Rat mAb (S-R198)Product Specification Host Rat Antigen RNA polymerase II CTD repeat YSPTSPS (phosphor S7) Synonyms DNA directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, DNA directed RNA polymerase II subunit A, DNA directed RNA polymerase III largest subunit, RNA directed RNA polymerase II subunit RPB1, POLR2A Location Cytoplasm, Nucleus Accession P24928 Clone Number S R198 Antibody Type Recombinant mAb Isotype IgG1 Application WB, ICC, IP
Product Specification
| Host | Rat |
| Antigen | RNA polymerase II CTD repeat YSPTSPS (phosphor S7) |
| Synonyms | DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1, POLR2A |
| Location | Cytoplasm, Nucleus |
| Accession | P24928 |
| Clone Number | S-R198 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1 |
| Application | WB, ICC, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein G |
| Concentration | 0.4 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:4000 | null |
| ICC | 1:100 | null |
| IP | 1:40 | null |
Background
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. The purified enzyme has typically 10–12 subunits (12 in humans and yeast). The subunit RPB1 contains a carboxy terminal domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity.
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